XIIDRA (lfifitegrast ophthalmic solution 5%) Patient Assistance Program

Don’t let the high cost of brand dry-eye therapy disrupt your treatment. We help eligible patients access Xiidra (lifitegrast ophthalmic solution 5%) for as little as $69.95 per month through the manufacturer’s Patient Assistance Program.

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Key ​Takeaways:

What Is Xiidra Prescription Assistance Program?

Xiidra PAP for dry eye disease.

Eligibility verification, ophthalmology/optometry coordination.

AffordMyPrescriptions eliminates that burden. $69.95/month advocacy.

Pharmacy Price Comparison

Pharmacy(With Coupon)PrIce (30-Day)*You Save W/ Us
Walgreens 

~$780

Save substantially

CVS Pharmacy

~$800

Save substantially

Walmart 

~$620

Save substantially

Costco

~$600

Save substantially

Generic cyclosporine

~$60

Generic Rx alt

*Just a heads-up — retail prices are estimates based on public data and vary by pharmacy. AffordMyPrescriptions Advocacy Service bypasses this by using drug manufacturer programs to secure your medication directly at no cost or retail price.

Our Pricing:

$69.95 Per month

1 Medications

$79.95 Per Month

2 Medications

$89.95 Per Month

3 Medications

$99.95 Per Month

4+ Medications

Why choose us For Your Xiidra Prescription Program?

OTC artificial tears, warm compresses, lid hygiene first-line. Generic cyclosporine (Restasis generic) much cheaper Rx alternative.

Enroll

Complete a simple eligibility form so our team can determine if you may qualify for medication assistance programs.

We Advocate

Our specialists help gather documentation, complete applications, and coordinate with program providers.

Receive Medication

Once approved, you may receive your medication through the assistance program while we help manage ongoing paperwork and renewals.

Discount Coupons vs. Patient Assistance Programs

Many patients try discount cards first. Here’s why the Patient Assistance Program through AffordMyPrescriptions is the better long-term solution for Xiidra:

Limitations of Coupons

  • Prices fluctuate — savings aren’t guaranteed month-to-month
  • Copay accumulators may prevent savings from counting toward deductible
  • Coupon cards expire and require constant renewal
  • Still $600–$800 per month even with the best discount

  • Can’t be used with Medicare, Medicaid, or government insurance

Advantages of PAP Through Us

  • Fixed $69.95/month — never changes regardless of retail price
  • No expiration — continuous access as long as you qualify
  • Medication supplied directly through the assistance program
  • We manage all paperwork, refills, and annual renewals
  • If denied, we  explore alternative savings on your behalf

DO YOU QUALIFY?

Eligibility is generally determined by annual household income and insurance status. Most programs follow guidelines that include limits of up to $40,000 for individuals, $60,000 for couples, and $100,000 for larger families. Because requirements vary by program and household, we encourage you to contact AffordMyPrescriptions directly so we can review your specific situation and determine if you qualify for Xiidra assistance.

Not sure if you qualify?  Our pre-qualification check is completely free. If we can’t help, you won’t be charged.

Understanding Xiidra:

Xiidra is LFA-1 antagonist — blocks T-cell binding to ICAM-1 in conjunctiva, reduces T-cell-mediated inflammation in dry eye. Twice-daily dosing.

How Xiidra Works:

Dry eye involves inflammation — T cells release cytokines that damage ocular surface.

Lifitegrast blocks LFA-1/ICAM-1 interaction — prevents T-cell recruitment and activation. Reduces ocular surface inflammation. Different mechanism from cyclosporine (calcineurin inhibitor) but both anti-inflammatory.

Form and use:

Xiidra 1 drop in each eye twice daily, approximately 12 hours apart.

Generic availability:

No generic Xiidra. Other Rx dry eye: cyclosporine 0.05% (Restasis — generic now available, much cheaper), cyclosporine 0.09% (Cequa), cyclosporine 0.1% (Vevye), perfluorohexyloctane (Miebo — evaporative), varenicline nasal spray (Tyrvaya), loteprednol 0.25% (Eysuvis — short-term flare). OTC artificial tears very cheap first-line.

Warnings:

Eye irritation, altered taste sensation (dysgeusia — common, transient), reduced visual acuity (transient), eye discomfort on instillation.

FAQ (Frequently Asked Questions)

Cost?

Xiidra $600–$800/month. Generic cyclosporine $50–$100. OTC tears $15.

Both anti-inflammatory. Restasis (cyclosporine) generic now available — much cheaper. Xiidra works faster for symptom relief (2 weeks vs months for Restasis). Some patients respond better to one or other. Generic cyclosporine often tried first now due to cost.

Xiidra anti-inflammatory; Miebo reduces evaporation. Different mechanisms. Some patients use combination.

Common — transient bitter/metallic taste after dosing. Usually well-tolerated.

Generic cyclosporine, OTC artificial tears, warm compresses, lid hygiene first-line.

Take Control of Your Medication Costs

Generic cyclosporine and OTC tears much cheaper first-line. Check eligibility today.

Submit Enrollment Form

Start free by filling out a simple online form.

Receive Welcome Call

Our specialist will contact you for a quick welcome call.

We Manage The Process

Our team handles everything, so you can focus on your health.

Receive Welcome Call

We Manage The Process