VIOKACE (pancrelipase, immediate-release) Patient Assistance Program

Don’t let the high cost of brand immediate-release pancreatic enzyme therapy disrupt your treatment. We help eligible patients access Viokace (pancrelipase, immediate-release) for as little as $69.95 per month through the manufacturer’s Patient Assistance Program.

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Key ​Takeaways:

What Is Viokace Prescription Assistance Program?

The Viokace Prescription Assistance Program is a manufacturer-sponsored initiative that provides Viokace at little or no medication cost to qualifying patients based on income and insurance status. The program is designed for exocrine pancreatic insufficiency patients who are uninsured or underinsured.

Navigating the program on your own means dealing with eligibility verification, gastroenterology coordination, prior-authorization documentation, specialty pharmacy logistics, and renewal deadlines.

AffordMyPrescriptions eliminates that burden. For a flat $69.95 per month, our Patient Advocates handle every step of your enrollment, from initial application through ongoing refill coordination and annual re-certification.

Pharmacy Price Comparison

Pharmacy(With Coupon)PrIce (30-Day)*You Save W/ Us
Walgreens

$480

Save ~$410/mo

CVS Pharmacy

~$500

Save ~$430/mo

Walmart 

~$350

Save ~$280/mo

Costco

~$330

Save ~$260/mo

Specialty Pharmacy

~$400

Save ~$330/mo

*Just a heads-up — retail prices are estimates based on public data and vary by pharmacy. AffordMyPrescriptions Advocacy Service bypasses this by using drug manufacturer programs to secure your medication directly at no cost or retail price.

Our Pricing:

$69.95 Per month

1 Medications

$79.95 Per Month

2 Medications

$89.95 Per Month

3 Medications

$99.95 Per Month

4+ Medications

Why choose us For Your Viokace Prescription Program?

The Patient Assistance Program is free to apply for and provides Viokace at no medication cost if approved. Our $69.95/month service covers full advocacy.

Enroll

Complete a simple eligibility form so our team can determine if you may qualify for medication assistance programs.

We Advocate

Our specialists help gather documentation, complete applications, and coordinate with program providers.

Receive Medication

Once approved, you may receive your medication through the assistance program while we help manage ongoing paperwork and renewals.

Discount Coupons vs. Patient Assistance Programs

Many patients try discount cards first. Here’s why the Patient Assistance Program through AffordMyPrescriptions is the better long-term solution for Viokace:

Limitations of Coupons

  • Prices fluctuate — savings aren’t guaranteed month-to-month
  • Copay accumulators may prevent savings from counting toward deductible
  • Coupon cards expire and require constant renewal
  • Still $300–$500 per month even with the best discount

  • Can’t be used with Medicare, Medicaid, or government insurance

Advantages of PAP Through Us

  • Fixed $69.95/month — never changes regardless of retail price
  • No expiration — continuous access as long as you qualify
  • Medication supplied directly through the assistance program
  • We manage all paperwork, refills, and annual renewals
  • If denied, we explore alternative savings on your behalf

DO YOU QUALIFY?

Eligibility is generally determined by annual household income and insurance status. Most programs follow guidelines that include limits of up to $40,000 for individuals, $60,000 for couples, and $100,000 for larger families. Because requirements vary by program and household, we encourage you to contact AffordMyPrescriptions directly so we can review your specific situation and determine if you qualify for Viokace assistance.

Not sure if you qualify?  Our pre-qualification check is completely free. If we can’t help, you won’t be charged.

Understanding Viokace:

Viokace is an immediate-release pancrelipase product — unlike other pancreatic enzyme replacement products that use enteric coatings to protect enzymes from gastric acid, Viokace tablets are not coated. Therefore, Viokace must be co-administered with a proton pump inhibitor (PPI) to suppress gastric acid and allow the enzymes to survive into the duodenum where they act.

How Viokace Works:

The pancreas normally secretes lipases, proteases, and amylases into the duodenum to digest fats, proteins, and carbohydrates, but exocrine pancreatic insufficiency reduces this output and causes malabsorption. Viokace provides a porcine-derived mixture of these essential digestive enzymes to restore normal breakdown of meals. Unlike delayed-release options, these immediate-release tablets release enzymes directly into the stomach, where gastric acid would normally destroy them. Because of this, Viokace must be taken with a proton pump inhibitor (PPI) to suppress stomach acid, allowing the active enzymes to safely reach the duodenum.

Form and use:

Viokace tablets must be taken orally with every single meal and snack a patient consumes. The typical adult dosage starts at 500 lipase units per kilogram per meal and is adjusted based on the patient’s symptoms. It is mandatory to co-administer Viokace with a PPI, such as omeprazole or esomeprazole, to successfully lower gastric acid levels. Finally, patients must swallow the tablets whole rather than crushing or chewing them.

Generic availability:

As of 2026, there is no generic version of Viokace available in the United States. Following a 2010 FDA mandate requiring these therapies to be regulated as new drugs, no generic pancrelipase products exist on the market. All available pancreatic enzyme replacement therapies in the U.S.—including both immediate-release options like Viokace and delayed-release brands like Zenpep, Creon, Pancreaze, and Pertzye—remain strictly brand-name products.

Warnings:

Viokace carries a warning for fibrosing colonopathy, a rare but serious scarring of the ascending colon that is associated with high doses and generally capped at 10,000 lipase units/kg/day. Due to the purine content in the porcine enzymes, it can cause hyperuricemia, and it can also trigger allergic hypersensitivity reactions to porcine protein. If the dosage is set too high, patients may experience severe constipation. Ultimately, failing to take the required concurrent PPI will render the Viokace treatment entirely ineffective.

FAQ (Frequently Asked Questions)

How Much Does Viokace Cost Without Insurance?

Viokace costs approximately $300–$500 per 30-day supply. Through AffordMyPrescriptions, qualifying patients receive Viokace at no medication cost — our $69.95 monthly fee covers full advocacy and program management.

Viokace tablets are immediate-release — without enteric coating, the digestive enzymes would be destroyed by stomach acid before reaching the duodenum where they need to act. A proton pump inhibitor (PPI — omeprazole, esomeprazole, etc.) suppresses gastric acid, allowing the enzymes to survive into the small intestine. PPI co-administration is essential for Viokace effectiveness.

Most patients with exocrine pancreatic insufficiency use delayed-release PERT products (Zenpep, Creon, Pancreaze, Pertzye) that don’t require concurrent PPI. Viokace is used in specific situations: when chronic pancreatitis is accompanied by significant abdominal pain (immediate-release enzymes may provide more pancreatic ‘rest’ effect via duodenal feedback), when delayed-release products have not provided adequate symptom relief, or based on individual prescriber preference. Discuss with your gastroenterologist whether Viokace’s regimen (Viokace + PPI) is the best fit for your situation.

Take at the START of every meal AND snack. Swallow tablets whole. Always take with the prescribed PPI (usually before meals as well). Without the PPI, enzymes are destroyed by gastric acid. Don’t crush or chew tablets. Stay hydrated. Watch for signs of inadequate dosing (continued steatorrhea, weight loss) or excessive dosing (constipation).

Signs of adequate dosing: formed stools (not greasy/oily), weight maintenance, resolution of bloating and abdominal pain, improved nutritional status. Signs of inadequate dosing: steatorrhea (oily floating stools), weight loss, continued abdominal symptoms. Periodic 72-hour fecal fat test may be done. Discuss adjustments with your gastroenterologist.

If denied, we explore alternatives — switching to a delayed-release PERT (Zenpep, Creon, Pancreaze, Pertzye) with its own PAP — which doesn’t require concurrent PPI — the manufacturer’s copay program for commercially insured patients, or independent foundations such as the National Pancreas Foundation, PAN Foundation, or HealthWell Foundation. If we cannot find a path, you won’t be charged our service fee.

If denied, we explore alternatives — switching to a dolutegravir combination tablet with its own PAP (Dovato, Triumeq, Juluca), state ADAP, the manufacturer’s copay program for commercially insured patients, or independent foundations. If we cannot find a path, you won’t be charged our service fee.

Take Control of Your Medication Costs

If denied, we explore alternatives — switching to a delayed-release PERT (Zenpep, Creon, Pancreaze, Pertzye) with its own PAP — which doesn’t require concurrent PPI — the manufacturer’s copay program for commercially insured patients, or independent foundations such as the National Pancreas Foundation, PAN Foundation, or HealthWell Foundation. If we cannot find a path, you won’t be charged our service fee.

Submit Enrollment Form

Start free by filling out a simple online form.

Receive Welcome Call

Our specialist will contact you for a quick welcome call.

We Manage The Process

Our team handles everything, so you can focus on your health.

Receive Welcome Call

We Manage The Process