RECARBRIO (imipenem/cilastatin/relebactam) Patient Assistance Program

Don’t let the high cost of brand specialty multi-drug-resistant gram-negative infection therapy disrupt your treatment. We help eligible patients access Recarbrio (imipenem/cilastatin/relebactam) for as little as $69.95 per month through the manufacturer’s Patient Assistance Program.

HIPAA Compliant

BBB Accredited

Secure Website

Key ​Takeaways:

What Is Recarbrio Prescription Assistance Program?

Recarbrio PAP for serious MDR gram-negative infections.

Eligibility, ID/hospital coordination.

AffordMyPrescriptions eliminates that burden. $69.95/month advocacy. 

Pharmacy Price Comparison

Pharmacy(With Coupon)PrIce (30-Day)*You Save W/ Us
Hospital pharmacy

~$750/dose

Save substantially

Inpatient billing

~$800/dose

Save substantially

Specialty Pharmacy

~$600/dose

Save substantially

Walmart

~$520/dose

Save substantially

Costco

~$510/dose

Save substantially

*Just a heads-up — retail prices are estimates based on public data and vary by pharmacy. AffordMyPrescriptions Advocacy Service bypasses this by using drug manufacturer programs to secure your medication directly at no cost or retail price.

Our Pricing:

$69.95 Per month

1 Medications

$79.95 Per Month

2 Medications

$89.95 Per Month

3 Medications

$99.95 Per Month

4+ Medications

Why choose us For Your Recarbrio Prescription Program?

PAP at no cost. Typically used inpatient — hospital billing coordination important.

Enroll

Complete a simple eligibility form so our team can determine if you may qualify for medication assistance programs.

We Advocate

Our specialists help gather documentation, complete applications, and coordinate with program providers.

Receive Medication

Once approved, you may receive your medication through the assistance program while we help manage ongoing paperwork and renewals.

Discount Coupons vs. Patient Assistance Programs

Many patients try discount cards first. Here’s why the Patient Assistance Program through AffordMyPrescriptions is the better long-term solution for Recarbrio:

Limitations of Coupons

  • Prices fluctuate — savings aren’t guaranteed month-to-month
  • Copay accumulators may prevent savings from counting toward deductible
  • Coupon cards expire and require constant renewal
  • Still $500–$800 per dose per month even with the best discount

  • Can’t be used with Medicare, Medicaid, or government insurance

Advantages of PAP Through Us

  • Fixed $69.95/month — never changes regardless of retail price
  • No expiration — continuous access as long as you qualify
  • Medication supplied directly through the assistance program
  • We manage all paperwork, refills, and annual renewals
  • If denied, we explore alternative savings on your behalf

DO YOU QUALIFY?

Eligibility is generally determined by annual household income and insurance status. Most programs follow guidelines that include limits of up to $40,000 for individuals, $60,000 for couples, and $100,000 for larger families. Because requirements vary by program and household, we encourage you to contact AffordMyPrescriptions directly so we can review your specific situation and determine if you qualify for Recarbrio assistance.

Not sure if you qualify?  Our pre-qualification check is completely free. If we can’t help, you won’t be charged.

Understanding Recarbrio:

Recarbrio combines imipenem (carbapenem antibiotic), cilastatin (renal dehydropeptidase inhibitor protecting imipenem), and relebactam (β-lactamase inhibitor). Active against many MDR gram-negative pathogens including some carbapenem-resistant Enterobacterales (CRE) — particularly those with KPC carbapenemases. Used inpatient for severe infections when limited alternatives exist.

How Recarbrio Works:

Recarbrio combines three components to fight multi-drug resistant gram-negative bacteria that produce destructive KPC carbapenemases. Imipenem functions as a standard $\beta$-lactam antibiotic that inhibits bacterial cell wall synthesis. Cilastatin is included to prevent the renal degradation of imipenem, effectively extending its half-life in the body. Finally, relebactam is a novel $\beta$-lactamase inhibitor that protects imipenem from inactivation by KPC and AmpC enzymes, thereby restoring its activity against resistant pathogens.

Form and use:

Recarbrio is administered exclusively as an intravenous (IV) infusion over a duration of 30 minutes. The standard dosing schedule requires the medication to be given every 6 hours. Depending on the specific indication and severity of the infection, a standard treatment course typically lasts between 7 and 14 days. Additionally, adjustments to the dosage are required for patients with renal impairment who have a creatinine clearance of less than 90.

Generic availability:

There is currently no generic version of Recarbrio available on the market. Clinicians looking for alternative treatments can consider other novel $\beta$-lactam/inhibitor combinations like ceftazidime/avibactam, meropenem/vaborbactam, ceftolozane/tazobactam, or cefiderocol. Each of these alternatives offers a unique spectrum of coverage against specific resistant pathogens and enzyme classes. Ultimately, choosing between them depends heavily on the specific resistance pattern, infection source, and infectious disease expertise.

Warnings:

Recarbrio carries severe warnings for serious hypersensitivity reactions, including anaphylaxis, requiring caution in patients with penicillin, cephalosporin, or carbapenem allergies. The medication can also lower the seizure threshold, particularly in patients with renal impairment, brain lesions, or concurrent valproate use. Furthermore, it significantly reduces valproate levels, meaning this drug combination should be avoided entirely. Finally, patients remain at risk for developing Clostridioides difficile-associated diarrhea and secondary superinfections.

FAQ (Frequently Asked Questions)

Cost?

$500–$800/dose. 7–14 day course $10,000–$22,000+. Hospital billing typically includes.

Reserved for serious infections with limited or no alternative treatments — typically MDR gram-negative pathogens (especially CRE with KPC carbapenemases). Inpatient use coordinated by ID specialist with culture/susceptibility data. Antimicrobial stewardship balances need vs. resistance preservation.

Other novel β-lactam/inhibitor combinations chosen based on resistance mechanism: Avycaz (avibactam — KPC, OXA-48 active), Vabomere (vaborbactam — KPC active), Zerbaxa (tazobactam — Pseudomonas/MDR), Fetroja (cefiderocol — broad including metallo-β-lactamases). ID consult guides choice.

Recarbrio is a carbapenem (β-lactam) — caution in severe β-lactam allergy. Discuss with ID team; allergy testing may be considered.

Imipenem (and other carbapenems) dramatically reduces valproate levels — risk of breakthrough seizures in patients on valproate for epilepsy. Avoid carbapenems if possible in patients on valproate; or use alternative anticonvulsant during carbapenem therapy.

Typically billed as part of hospitalization. PAP and copay programs may help with high-deductible plans or uninsured.

ID consult to assess alternatives based on susceptibilities. Hospital charity programs. PAP if uninsured. Other novel agents may be available.

Take Control of Your Medication Costs

If facing Recarbrio cost from hospital MDR gram-negative infection, we can help coordinate manufacturer PAP and hospital billing assistance. Check eligibility today.

Submit Enrollment Form

Start free by filling out a simple online form.

Receive Welcome Call

Our specialist will contact you for a quick welcome call.

We Manage The Process

Our team handles everything, so you can focus on your health.

Receive Welcome Call

We Manage The Process