PRIFTIN (rifapentine) Patient Assistance Program
Don’t let the high cost of brand TB therapy disrupt your treatment. We help eligible patients access Priftin (rifapentine) for as little as $69.95 per month through the manufacturer’s Patient Assistance Program.
- Clear & Transparent Pricing
- Paperwork & Doctor-Coordination
- Comprehensive Support: From Application to Entire Journey.
- Annual Re-certification And Refills Management
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Key Takeaways:
- Priftin (rifapentine) is FDA-approved for the treatment of active pulmonary tuberculosis caused by drug-susceptible M. tuberculosis (in combination with other antitubercular drugs) and for treatment of latent tuberculosis infection (LTBI) in patients ≥2 years (in combination with isoniazid as the 12-dose once-weekly 3HP regimen).
- Without assistance, Priftin costs commonly run approximately $400–$800 per course of LTBI therapy.
- Through AffordMyPrescriptions, qualifying patients can access Priftin for a flat $69.95 per month.
- Generic rifapentine is now available at substantially lower cost. State/local public health TB programs often provide free LTBI and active TB treatment regardless of insurance status. The 3HP regimen (12 weekly doses of isoniazid + rifapentine) is the preferred LTBI treatment for most patients due to short duration and high completion rates.
What Is Priftin Prescription Assistance Program?
Priftin PAP for TB/LTBI patients.
Eligibility, ID/TB clinic/public health coordination.
AffordMyPrescriptions eliminates that burden. $69.95/month advocacy.
Pharmacy Price Comparison
- Priftin $400–$800/course. Generic rifapentine and public health TB programs help:
| Pharmacy(With Coupon) | PrIce (30-Day)* | You Save W/ Us |
|---|---|---|
| Walgreens (brand) | ~$750/course | Save substantially |
| CVS Pharmacy (brand) | ~$800/course | Save substantially |
| Walmart (brand) | ~$450/course | Save substantially |
| Costco (brand) | ~$430/course | Save substantially |
Public health TB program | Often free | TB priority |
*Just a heads-up — retail prices are estimates based on public data and vary by pharmacy. AffordMyPrescriptions Advocacy Service bypasses this by using drug manufacturer programs to secure your medication directly at no cost or retail price.
Our Pricing:
$69.95 Per month
1 Medications
$79.95 Per Month
2 Medications
$89.95 Per Month
3 Medications
$99.95 Per Month
4+ Medications
Why choose us For Your Priftin Prescription Program?
PAP at no cost. Public health TB programs often provide LTBI and active TB treatment regardless of insurance.
Enroll
Complete a simple eligibility form so our team can determine if you may qualify for medication assistance programs.
We Advocate
Our specialists help gather documentation, complete applications, and coordinate with program providers.
Receive Medication
Once approved, you may receive your medication through the assistance program while we help manage ongoing paperwork and renewals.
Discount Coupons vs. Patient Assistance Programs
Many patients try discount cards first. Here’s why the Patient Assistance Program through AffordMyPrescriptions is the better long-term solution for Priftin:
Limitations of Coupons
- Prices fluctuate — savings aren’t guaranteed month-to-month
- Copay accumulators may prevent savings from counting toward deductible
- Coupon cards expire and require constant renewal
Still $400–$800 per course per month even with the best discount
- Can’t be used with Medicare, Medicaid, or government insurance
Advantages of PAP Through Us
- Fixed $69.95/month — never changes regardless of retail price
- No expiration — continuous access as long as you qualify
- Medication supplied directly through the assistance program
- We manage all paperwork, refills, and annual renewals
- If denied, we explore alternative savings on your behalf
DO YOU QUALIFY?
Eligibility is generally determined by annual household income and insurance status. Most programs follow guidelines that include limits of up to $40,000 for individuals, $60,000 for couples, and $100,000 for larger families. Because requirements vary by program and household, we encourage you to contact AffordMyPrescriptions directly so we can review your specific situation and determine if you qualify for Priftin assistance.
- You Are A U.S. Citizen Or Legal Resident
- You Have A Valid Priftin Prescription From A Licensed U.S. Healthcare Provider
- You Are Uninsured Or Underinsured And Cannot Afford Your Medication
- You Have Recently Experienced A Change In Financial Circumstances That Affects Your Ability To Pay
Not sure if you qualify? Our pre-qualification check is completely free. If we can’t help, you won’t be charged.
Understanding Priftin:
Priftin (rifapentine) is a rifamycin antitubercular antibiotic with longer half-life than rifampin — allowing once-weekly dosing in latent TB treatment (the 3HP regimen) and twice-weekly intermittent dosing in continuation phase of active TB.
How Priftin Works:
Rifamycins bind bacterial DNA-dependent RNA polymerase, inhibiting transcription. Active against drug-susceptible M. tuberculosis. Rifapentine’s long half-life (~13 hours vs rifampin ~3 hours) allows less-frequent dosing.
3HP regimen for LTBI: 12 once-weekly doses of isoniazid 15 mg/kg + rifapentine 900 mg (for adults ≥50 kg) under directly observed therapy or self-administered. Preferred over older 9-month daily isoniazid (9H regimen) due to shorter duration and equivalent efficacy with higher completion rates.
Form and use:
For LTBI 3HP regimen: rifapentine 900 mg + isoniazid 15 mg/kg once weekly for 12 weeks. For active TB: complex regimens including rifapentine — coordinated by TB specialist.
Generic availability:
Generic rifapentine now available. Generic isoniazid widely available very cheap. For LTBI, generic isoniazid daily for 9 months (9H) is the cheapest option but lower completion rates. Other LTBI options: rifampin daily for 4 months (4R), rifampin + isoniazid daily for 3 months (3HR).
Warnings:
Priftin warnings: hepatotoxicity (especially with isoniazid combination — LFT monitoring), hypersensitivity reactions and flu-like syndrome with intermittent dosing, hemolysis and thrombocytopenia (rare), drug interactions (CYP3A4 inducer — reduces levels of MANY medications including hormonal contraceptives, warfarin, many others — backup contraception recommended), peripheral neuropathy (with isoniazid; vitamin B6/pyridoxine supplementation recommended), orange-red discoloration of body fluids (urine, tears, sweat — harmless but can stain contact lenses).
FAQ (Frequently Asked Questions)
Cost ?
Brand $400–$800/course. Generic rifapentine cheaper. Public health TB programs often free.
Public health TB program?
Latent and active TB treatment are public health priorities. State/local TB programs often provide medication, monitoring, directly observed therapy regardless of insurance. Contact your local TB control program for any positive TB skin test or IGRA, or for active TB diagnosis.
3HP vs 9H?
3HP (12 once-weekly doses of isoniazid + rifapentine): shorter, better completion rates, preferred for most patients. 9H (9 months daily isoniazid): older, very cheap, lower completion rates. 3HP is the preferred regimen for most LTBI per current CDC guidelines.
Drug interactions?
Rifapentine is a CYP3A4 inducer — substantially reduces levels of: hormonal contraceptives (use backup non-hormonal), warfarin, many HIV medications, methadone, statins, glucocorticoids, many others. Tell every prescriber about rifapentine.
Orange-red urine?
Yes — harmless side effect from rifapentine. Body fluids (urine, tears, sweat) turn orange-red. Don’t wear soft contact lenses (can stain permanently). Resolves after stopping medication.
Vitamin B6?
Pyridoxine (vitamin B6) 25–50 mg/day usually given with isoniazid to prevent peripheral neuropathy. Especially important in pregnancy, breastfeeding, diabetes, alcohol use, malnutrition.
Denied?
Generic rifapentine, public health TB program (free), generic isoniazid 9H alternative.
Take Control of Your Medication Costs
If facing Priftin cost, contact public health TB program first — typically free for documented LTBI/TB. Check eligibility today.
Submit Enrollment Form
Start free by filling out a simple online form.
Receive Welcome Call
Our specialist will contact you for a quick welcome call.
We Manage The Process
Our team handles everything, so you can focus on your health.