PRETOMANID (pretomanid) Patient Assistance Program
Don’t let the high cost of brand specialty XDR-TB therapy disrupt your treatment. We help eligible patients access Pretomanid (pretomanid) for as little as $69.95 per month through the manufacturer’s Patient Assistance Program.
- Clear & Transparent Pricing
- Paperwork & Doctor-Coordination
- Comprehensive Support: From Application to Entire Journey.
- Annual Re-certification And Refills Management
- Medicare Part D Patients Accepted
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Key Takeaways:
- Pretomanid is FDA-approved in combination with bedaquiline (Sirturo) and linezolid as the BPaL regimen for treatment of pulmonary extensively drug-resistant (XDR-TB), treatment-intolerant, or non-responsive multidrug-resistant tuberculosis (MDR-TB) in adults. 6-month all-oral regimen for highly drug-resistant TB — major advance over previous 18–24 month regimens.
- Without assistance, Pretomanid costs commonly run approximately $4,000–$6,000 per 6-month course.
- Through AffordMyPrescriptions, qualifying patients can access Pretomanid for a flat $69.95 per month.
- TB Alliance distributes Pretomanid through specialized channels. State and local TB programs and the CDC TB program coordinate access for MDR/XDR-TB patients. Coordinated through specialized TB treatment centers.
What Is Pretomanid Prescription Assistance Program?
Pretomanid PAP for MDR/XDR-TB patients.
Eligibility, ID/TB clinic/public health TB program coordination.
AffordMyPrescriptions eliminates that burden. $69.95/month advocacy.
Pharmacy Price Comparison
- Pretomanid $4,000–$6,000/course. State TB programs and PAP help:
| Pharmacy(With Coupon) | PrIce (30-Day)* | You Save W/ Us |
|---|---|---|
| Walgreens | ~$5,500/course | Save substantially |
| CVS Pharmacy | ~$6,000/course | Save substantially |
| Walmart | ~$4,300/course | Save substantially |
| Costco | ~$4,200/course | Save substantially |
State TB program | Often free | MDR-TB programs |
*Just a heads-up — retail prices are estimates based on public data and vary by pharmacy. AffordMyPrescriptions Advocacy Service bypasses this by using drug manufacturer programs to secure your medication directly at no cost or retail price.
Our Pricing:
$69.95 Per month
1 Medications
$79.95 Per Month
2 Medications
$89.95 Per Month
3 Medications
$99.95 Per Month
4+ Medications
Why choose us For Your Pretomanid Prescription Program?
PAP at no cost. State and local TB programs typically coordinate MDR/XDR-TB therapy regardless of insurance — public health priority.
Enroll
Complete a simple eligibility form so our team can determine if you may qualify for medication assistance programs.
We Advocate
Our specialists help gather documentation, complete applications, and coordinate with program providers.
Receive Medication
Once approved, you may receive your medication through the assistance program while we help manage ongoing paperwork and renewals.
Discount Coupons vs. Patient Assistance Programs
Many patients try discount cards first. Here’s why the Patient Assistance Program through AffordMyPrescriptions is the better long-term solution for Pretomanid:
Limitations of Coupons
- Prices fluctuate — savings aren’t guaranteed month-to-month
- Copay accumulators may prevent savings from counting toward deductible
- Coupon cards expire and require constant renewal
Still $4,000–$6,000 per 6-month course per month even with the best discount
- Can’t be used with Medicare, Medicaid, or government insurance
Advantages of PAP Through Us
- Fixed $69.95/month — never changes regardless of retail price
- No expiration — continuous access as long as you qualify
- Medication supplied directly through the assistance program
- We manage all paperwork, refills, and annual renewals
- If denied, we explore alternative savings on your behalf
DO YOU QUALIFY?
Eligibility is generally determined by annual household income and insurance status. Most programs follow guidelines that include limits of up to $40,000 for individuals, $60,000 for couples, and $100,000 for larger families. Because requirements vary by program and household, we encourage you to contact AffordMyPrescriptions directly so we can review your specific situation and determine if you qualify for Pretomanid assistance.
- You Are A U.S. Citizen Or Legal Resident
- You Have A Valid Pretomanid Prescription From A Licensed U.S. Healthcare Provider
- You Are Uninsured, Underinsured, Or A Medicare Part D Beneficiary
- You Have Recently Experienced A Change In Financial Circumstances That Affects Your Ability To Pay
Not sure if you qualify? Our pre-qualification check is completely free. If we can’t help, you won’t be charged.
Understanding Pretomanid:
Pretomanid is a nitroimidazooxazine antimycobacterial used as part of the BPaL regimen (Bedaquiline + Pretomanid + Linezolid) for XDR-TB and treatment-intolerant or non-responsive MDR-TB. This 6-month all-oral regimen has transformed treatment of highly drug-resistant TB — vs. the older 18–24 month injectable regimens.
How Pretomanid Works:
XDR-TB resists isoniazid, rifampin, fluoroquinolones, AND injectable second-line drugs — historically very difficult to treat (cure rates 30–50%, 2 years of toxic therapy). The BPaL regimen revolutionized this: 89% cure rate at 6 months with all-oral therapy.
Pretomanid is activated by mycobacterial deazaflavin-dependent nitroreductase (Ddn) to nitric oxide and other metabolites that kill TB bacteria. Active against replicating and non-replicating M. tuberculosis. The synergistic BPaL combination targets TB at multiple metabolic steps for rapid sterilization.
Form and use:
Pretomanid 200 mg once daily by mouth, with food (food significantly increases absorption). Given as part of BPaL regimen: bedaquiline (varying schedule), pretomanid (daily x 6 months), linezolid (daily x 6 months). Total 6-month course.
Generic availability:
No generic. Pretomanid is developed by TB Alliance (non-profit). The CDC and state/local TB programs coordinate access. BPaL regimen now widely adopted for XDR-TB and treatment-intolerant MDR-TB. Variations: BPaLM (adds moxifloxacin) for some MDR-TB; ongoing research for shorter regimens.
Warnings:
Pretomanid carries warnings for hepatotoxicity (LFT monitoring required), peripheral and optic neuropathy (mainly from concurrent linezolid; monitor neurologic and visual function), myelosuppression (mainly from linezolid; CBC monitoring), QT prolongation (mainly from bedaquiline), reproductive toxicity in males (decreased fertility — counsel male patients), and rare hypersensitivity.
FAQ (Frequently Asked Questions)
Cost?
Pretomanid alone $4,000–$6,000 per 6-month course. Full BPaL regimen (with bedaquiline, linezolid) more expensive. State TB programs often coordinate free access for MDR/XDR-TB.
BPaL regimen?
Bedaquiline + Pretomanid + Linezolid — 6-month all-oral regimen for XDR-TB and treatment-intolerant MDR-TB. ~89% cure rate vs ~30–50% historical with older regimens. Major advance for highly drug-resistant TB.
Public health programs?
MDR/XDR-TB is a public health priority. State and local TB programs coordinate diagnosis, treatment, and directly observed therapy regardless of insurance status. Contact your state TB control program for any MDR/XDR-TB case.
Drug interactions?
Pretomanid is a CYP3A4 substrate. Major concerns: linezolid + serotonergic agents (serotonin syndrome), bedaquiline + QT-prolonging drugs. TB physician coordinates complex interactions.
Side effects?
Complex multi-drug regimen — peripheral neuropathy and optic neuropathy (mainly linezolid; baseline and follow-up testing), myelosuppression (CBC every 1–2 weeks), hepatotoxicity, QT prolongation, lactic acidosis (linezolid).
Pregnancy?
Limited data. Pretomanid causes male reproductive toxicity. Discuss with TB physician — TB therapy in pregnancy is complex.
Denied?
State TB programs typically provide MDR/XDR-TB therapy regardless of insurance. TB Alliance access program. CDC TB program. Public health priority for access.
Take Control of Your Medication Costs
If facing Pretomanid cost for MDR/XDR-TB, contact state TB program immediately — public health priority. Our advocacy helps coordinate. Check eligibility today.
Submit Enrollment Form
Start free by filling out a simple online form.
Receive Welcome Call
Our specialist will contact you for a quick welcome call.
We Manage The Process
Our team handles everything, so you can focus on your health.