Gleostine (lomustine) Patient Assistance Program
Don’t let the high cost of brand alkylating chemotherapy disrupt your treatment. We help eligible patients access Gleostine (lomustine) for as little as $69.95 per month through the manufacturer’s Patient Assistance Program.
- Clear & Transparent Pricing
- Paperwork & Doctor-Coordination
- Comprehensive Support: From Application to Entire Journey.
- Annual Re-certification And Refills Management
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Key Takeaways:
- Gleostine (lomustine, formerly CeeNU) is FDA-approved for brain tumors (primary and metastatic) and Hodgkin lymphoma after failure of conventional therapy. Lipid-soluble alkylating agent that crosses blood-brain barrier — useful for CNS malignancies.
- Without assistance, brand Gleostine costs commonly run approximately $1,500–$3,000 per cycle (every 6 weeks).
- Through AffordMyPrescriptions, qualifying patients can access Gleostine for a flat $69.95 per month.
- Generic lomustine became available after CeeNU was rebranded as Gleostine (with price increase). Generic lomustine substantially cheaper. Notably, Gleostine had massive price increases (~1500% from $50 to $750+ per capsule) after rebrand from CeeNU — case study in problematic drug pricing.
What Is Gleostine Prescription Assistance Program?
Gleostine PAP for brain tumor/lymphoma patients.
Eligibility, oncology coordination.
AffordMyPrescriptions eliminates that burden. $69.95/month advocacy.
Pharmacy Price Comparison
- Gleostine $1,500–$3,000/cycle. Generic lomustine cheaper:
| Pharmacy(With Coupon) | PrIce (30-Day)* | You Save W/ Us |
|---|---|---|
| Walgreens (brand) | ~$2,800/cycle | Save substantially |
| CVS Pharmacy (brand) | ~$3,000/cycle | Save substantially |
| Walmart (brand) | ~$1,600/cycle | Save substantially |
| Costco (brand) | ~$1,550/cycle | Save substantially |
Generic imatinib | ~$500/cycle | Generic — lower |
*Just a heads-up — retail prices are estimates based on public data and vary by pharmacy. AffordMyPrescriptions Advocacy Service bypasses this by using drug manufacturer programs to secure your medication directly at no cost or retail price.
Our Pricing:
$69.95 Per month
1 Medications
$79.95 Per Month
2 Medications
$89.95 Per Month
3 Medications
$99.95 Per Month
4+ Medications
Why choose us For Your Gleostine Prescription Program?
Generic lomustine substantially cheaper than brand Gleostine. Gleostine pricing controversy a notable case in drug pricing literature.
Enroll
Complete a simple eligibility form so our team can determine if you may qualify for medication assistance programs.
We Advocate
Our specialists help gather documentation, complete applications, and coordinate with program providers.
Receive Medication
Once approved, you may receive your medication through the assistance program while we help manage ongoing paperwork and renewals.
Discount Coupons vs. Patient Assistance Programs
Many patients try discount cards first. Here’s why the Patient Assistance Program through AffordMyPrescriptions is the better long-term solution for Gleostine:
Limitations of Coupons
- Prices fluctuate — savings aren’t guaranteed month-to-month
- Copay accumulators may prevent savings from counting toward deductible
- Coupon cards expire and require constant renewal
Still $1,500–$3,000/cycle per month even with the best discount
- Can’t be used with Medicare, Medicaid, or government insurance
Advantages of PAP Through Us
- Fixed $69.95/month — never changes regardless of retail price
- No expiration — continuous access as long as you qualify
- Medication supplied directly through the assistance program
- We manage all paperwork, refills, and annual renewals
- If denied, we explore alternative savings on your behalf
DO YOU QUALIFY?
Eligibility is generally determined by annual household income and insurance status. Most programs follow guidelines that include limits of up to $40,000 for individuals, $60,000 for couples, and $100,000 for larger families. Because requirements vary by program and household, we encourage you to contact AffordMyPrescriptions directly so we can review your specific situation and determine if you qualify for Gleostine assistance.
- You Are A U.S. Citizen Or Legal Resident
- You Have A Valid Gleostine Prescription From A Licensed U.S. Healthcare Provider
- You Are Uninsured Or Underinsured And Cannot Afford Your Medication
- You Have Recently Experienced A Change In Financial Circumstances That Affects Your Ability To Pay
Not sure if you qualify? Our pre-qualification check is completely free. If we can’t help, you won’t be charged.
Understanding Gleostine:
Gleostine (lomustine) is oral nitrosourea alkylating agent. Highly lipid-soluble — crosses blood-brain barrier for CNS tumor treatment. Single dose every 6 weeks. Originally branded CeeNU at low cost; rebranded Gleostine with massive price increase 2013–2014.
How Gleostine Works:
Lomustine spontaneously decomposes generating carbamoylating and alkylating species — cross-links DNA causing strand breaks and apoptosis. Activity against rapidly proliferating cancer cells.
Lipophilic properties allow CNS penetration — useful for primary brain tumors (gliomas) and CNS lymphoma. Combined with other agents (PCV regimen for low-grade gliomas: procarbazine + lomustine + vincristine; combined with TMZ for high-grade gliomas).
Form and use:
Generic lomustine substantially cheaper than brand. Gleostine pricing controversy: in 2013, CytRx Corp sold lomustine to NextSource which rebranded as Gleostine — price went from ~$50 to ~$750/capsule. Pattern of orphan drug acquisition + price increase. Generic relief eventually.
Generic availability:
BOXED WARNING for delayed myelosuppression (CBC nadir 4–6 weeks post-dose; severe neutropenia and thrombocytopenia common; can be fatal — monitor every 6 weeks before re-dosing), secondary malignancies (especially leukemia), pulmonary toxicity (pulmonary fibrosis with cumulative dose >1100 mg/m² in adults), hepatotoxicity, nephrotoxicity (cumulative), nausea/vomiting (severe — antiemetics essential).
Warnings:
Gleevec carries notable warnings for edema and severe fluid retention, which can manifest dangerously as pulmonary edema, pleural or pericardial effusions, and ascites. It is associated with cytopenias, hepatotoxicity, and gastrointestinal bleeding or perforation, alongside a risk of tumor lysis syndrome right at the start of therapy. Patients with existing cardiac risk factors face a risk of cardiomyopathy and congestive heart failure, while thyroidectomized patients taking levothyroxine risk developing hypothyroidism. Finally, the medication carries warnings for dermatologic toxicity, embryo-fetal toxicity, and significant drug interactions with both CYP3A4 inhibitors and inducers.
FAQ (Frequently Asked Questions)
Cost?
Brand Gleostine $1,500–$3,000/cycle. Generic $300–$700. Original CeeNU was $50 before rebrand.
Gleostine pricing?
When rebranded from CeeNU (2013), price increased ~1500% from $50/capsule to $750+/capsule. Notable example of orphan drug pricing exploitation. Generic eventually provided relief.
Why every 6 weeks?
Delayed myelosuppression — nadir 4–6 weeks post-dose. Must wait for CBC recovery (ANC >1500, platelets >100,000) before next dose. Boxed warning.
Brain tumor regimens?
Lomustine used in PCV (procarbazine + lomustine + vincristine) for low-grade glioma. Combined with TMZ for some high-grade gliomas. Single agent for recurrent disease
Cumulative toxicity?
Pulmonary fibrosis risk increases with cumulative dose >1100 mg/m² in adults. Plan total lifetime exposure carefully.
Denied?
Generic lomustine, manufacturer copay, foundation aid. National Brain Tumor Society resources.
Take Control of Your Medication Costs
Generic lomustine substantially cheaper than brand Gleostine. Check eligibility today.
Submit Enrollment Form
Start free by filling out a simple online form.
Receive Welcome Call
Our specialist will contact you for a quick welcome call.
We Manage The Process
Our team handles everything, so you can focus on your health.