DIPENTUM (folsalazine sodium) Patient Assistance Program
Don’t let the high cost of brand colonic 5-ASA therapy disrupt your IBD maintenance. We help eligible patients access Dipentum (olsalazine sodium) for as little as $69.95 per month through the manufacturer’s Patient Assistance Program.
- Clear & Transparent Pricing
- Paperwork & Doctor-Coordination
- Comprehensive Support: From Application to Entire Journey.
- Annual Re-certification And Refills Management
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Key Takeaways:
- Dipentum (olsalazine sodium) is FDA-approved for the maintenance of remission of ulcerative colitis (UC) in patients who are intolerant of sulfasalazine. It is a prodrug — two molecules of 5-aminosalicylic acid (5-ASA, mesalamine) linked by an azo bond that is cleaved by colonic bacteria to release 5-ASA directly in the colon.
- Without assistance, brand Dipentum costs commonly run approximately $500–$700 per 30-day supply.
- Through AffordMyPrescriptions, qualifying patients can access Dipentum for a flat $69.95 per month — our advocacy team manages the entire enrollment, refills, and renewal process.
- Generic olsalazine sodium is available in the U.S. at lower cost. Other oral 5-ASA products: mesalamine controlled-release (Pentasa, generic — small bowel and colon), mesalamine colon-targeted (Asacol HD/Delzicol, Lialda, Apriso — all with generics), sulfasalazine (generic, very cheap — but intolerance is common). Balsalazide (Colazal, generic) is another azo-linked prodrug similar to Dipentum.
What Is Dipentum Prescription Assistance Program?
The Dipentum Prescription Assistance Program is a manufacturer-sponsored initiative that provides Dipentum at little or no medication cost to qualifying patients based on income and insurance status. The program is designed for UC maintenance patients who are uninsured or underinsured.
Navigating the program on your own means dealing with eligibility verification, gastroenterology coordination, prior-authorization documentation, and renewal deadlines.
AffordMyPrescriptions eliminates that burden. For a flat $69.95 per month, our Patient Advocates handle every step of your enrollment, from initial application through ongoing refill coordination and annual re-certification.
Pharmacy Price Comparison
- Without assistance, brand Dipentum costs roughly $500–$700/month. Generic olsalazine is cheaper. A Patient Assistance Program is the meaningful path forward — if you qualify:
| Pharmacy(With Coupon) | PrIce (30-Day)* | You Save W/ Us |
|---|---|---|
| Walgreens (brand) | ~$680 | Save ~$610/mo |
| CVS Pharmacy (brand) | ~$700 | Save ~$630/mo |
| Walmart (brand) | ~$540 | Save ~$470/mo |
| Costco (brand) | ~$520 | Save ~$450/mo |
Generic olsalazine | ~$200 | Generic — lower |
*Just a heads-up — retail prices are estimates based on public data and vary by pharmacy. AffordMyPrescriptions Advocacy Service bypasses this by using drug manufacturer programs to secure your medication directly at no cost or retail price.
Our Pricing:
$69.95 Per month
1 Medications
$79.95 Per Month
2 Medications
$89.95 Per Month
3 Medications
$99.95 Per Month
4+ Medications
Why choose us For Your Dipentum Prescription Program?
The Patient Assistance Program is free to apply for and provides Dipentum at no medication cost if approved. Our $69.95/month service covers full advocacy. With generic olsalazine and many other oral mesalamine alternatives available at low cost, we’ll help your gastroenterologist determine the best path.
Enroll
Complete a simple eligibility form so our team can determine if you may qualify for medication assistance programs.
We Advocate
Our specialists help gather documentation, complete applications, and coordinate with program providers.
Receive Medication
Once approved, you may receive your medication through the assistance program while we help manage ongoing paperwork and renewals.
Discount Coupons vs. Patient Assistance Programs
Many patients try discount cards first. Here’s why the Patient Assistance Program through AffordMyPrescriptions is the better long-term solution for Dipentum:
Limitations of Coupons
- Prices fluctuate — savings aren’t guaranteed month-to-month
- Copay accumulators may prevent savings from counting toward deductible
- Coupon cards expire and require constant renewal
Still $500–$700 per month even with the best discount
- Can’t be used with Medicare, Medicaid, or government insurance
Advantages of PAP Through Us
- Fixed $69.95/month — never changes regardless of retail price
- No expiration — continuous access as long as you qualify
- Medication supplied directly through the assistance program
- We manage all paperwork, refills, and annual renewals
- If denied, we explore alternative savings on your behalf
DO YOU QUALIFY?
Eligibility is generally determined by annual household income and insurance status. Most programs follow guidelines that include limits of up to $40,000 for individuals, $60,000 for couples, and $100,000 for larger families. Because requirements vary by program and household, we encourage you to contact AffordMyPrescriptions directly so we can review your specific situation and determine if you qualify for Dipentum assistance.
- You Are A U.S. Citizen Or Legal Resident
- You Have A Valid Dipentum Tablets Prescription From A Licensed U.S. Healthcare Provider
- You Are Uninsured Or Underinsured And Cannot Afford Your Medication
- You Have Recently Experienced A Change In Financial Circumstances That Affects Your Ability To Pay
Not sure if you qualify? Our pre-qualification check is completely free. If we can’t help, you won’t be charged.
Understanding Dipentum:
Dificid (fidaxomicin) is narrow-spectrum macrocyclic antibiotic targeting C. difficile while preserving normal gut microbiome. First-line CDI treatment per IDSA/SHEA 2021 guidelines — reduces recurrence vs oral vancomycin.
How Dipentum works:
Sulfasalazine was the original 5-ASA prodrug — sulfapyridine linked to 5-ASA, cleaved by colonic bacteria. Sulfasalazine releases sulfapyridine, which is responsible for most of its side effects (rash, nausea, headache, hemolysis, infertility in males). Many patients become intolerant of sulfasalazine over time.
Olsalazine (Dipentum) was designed as a sulfa-free alternative — it links 5-ASA to itself via an azo bond, releasing two molecules of 5-ASA in the colon (and no sulfapyridine). 5-ASA reduces colonic inflammation through multiple mechanisms (inhibition of leukotriene/prostaglandin synthesis, PPARγ activation, NF-κB inhibition). The most common side effect of olsalazine — secretory diarrhea — limits its use for some patients.
Form and use:
Dipentum is taken as 500 mg twice daily by mouth for UC maintenance — typical dose 1 g/day in 2 divided doses. Take with food to reduce GI side effects. Drink plenty of fluids. Do not crush or chew capsules.
Generic availability:
Generic olsalazine sodium is available in the U.S. at lower cost than brand Dipentum. Other oral 5-ASA products: mesalamine controlled-release capsules (Pentasa, generic — small bowel and colon release), mesalamine pH-dependent tablets (Asacol HD/Delzicol, generic — colon-targeted), Lialda (mesalamine MMX, once-daily, generic — colonic), Apriso (mesalamine, once-daily, generic), and balsalazide (Colazal, generic — another azo-linked sulfa-free prodrug similar to olsalazine). Sulfasalazine (generic, very cheap — but intolerance is common). Most patients can access a 5-ASA product at low cost via generics.
Warnings:
Dipentum carries warnings for secretory diarrhea (very common — affects ~17% of patients; often the limiting side effect; usually responds to dose reduction or temporary discontinuation), renal impairment (rare interstitial nephritis with the 5-ASA class — periodic renal monitoring), hypersensitivity reactions, pancreatitis (rare), pericarditis/myocarditis (rare), and severe cutaneous reactions including Stevens-Johnson syndrome (rare).
FAQ (Frequently Asked Questions)
How Much Does Dipentum Cost Without Insurance?
Brand Dipentum costs approximately $500–$700 per 30-day supply. Generic olsalazine is cheaper. Through AffordMyPrescriptions, qualifying patients receive Dipentum at no medication cost — our $69.95 monthly fee covers full advocacy and program management.
Why Was Dipentum Prescribed Instead Of Other Mesalamines?
Dipentum is FDA-approved specifically for UC maintenance in patients who are intolerant of sulfasalazine. The 5-ASA component is the same as in other mesalamine products, but the delivery method (azo-linked prodrug cleaved by colonic bacteria) differs from pH-dependent or time-dependent oral mesalamines. Choice between Dipentum and other 5-ASAs (Pentasa, Asacol, Lialda) often depends on insurance coverage and side-effect profile
Why The Diarrhea On Dipentum?
Olsalazine causes secretory diarrhea (different from UC-related diarrhea) in about 17% of patients — likely due to a direct effect of olsalazine on intestinal water/electrolyte secretion. Often the limiting side effect. Taking Dipentum with food, dose reduction, or temporary discontinuation typically helps. Tell your gastroenterologist about persistent or new-onset diarrhea that doesn’t match your usual UC pattern.
How Is Dipentum Different From Sulfasalazine?
Both are azo-linked 5-ASA prodrugs cleaved by colonic bacteria. Sulfasalazine releases 5-ASA AND sulfapyridine — sulfapyridine causes most sulfasalazine side effects (rash, nausea, headache, hemolysis, infertility in males). Dipentum releases two 5-ASAs and no sulfapyridine — eliminating the sulfa-related side effects but adding the olsalazine-specific secretory diarrhea. Dipentum is specifically indicated for sulfasalazine-intolerant patients.
Can Dipentum Be Used For Active Disease, Not Just Maintenance?
Dipentum is FDA-approved for UC maintenance specifically. For active disease, other 5-ASA products (Pentasa, Asacol, Lialda) and topical treatments (Rowasa enemas, Canasa suppositories) are typically used at higher doses with the addition of corticosteroids or other agents if needed. Discuss with your gastroenterologist.
What If My Application Is Denied?
If denied, we explore alternatives — switching to generic olsalazine, generic balsalazide (Colazal — similar azo-linked sulfa-free 5-ASA), generic mesalamine (Pentasa, Asacol, Lialda, Apriso — many generics available), generic sulfasalazine if tolerated, the manufacturer’s copay program for commercially insured patients, or independent foundations such as the Crohn’s & Colitis Foundation, PAN Foundation, or HealthWell Foundation. If we cannot find a path, you won’t be charged our service fee.
Take Control of Your Medication Costs
If you are struggling with the high cost of Dipentum, our team may be able to help you access assistance programs — or guide you to generic olsalazine or another 5-ASA option. Check your eligibility today.
Submit Enrollment Form
Start free by filling out a simple online form.
Receive Welcome Call
Our specialist will contact you for a quick welcome call.
We Manage The Process
Our team handles everything, so you can focus on your health.