Cabenuva Patient Assistance Program
Don’t let the high cost of brand long-acting HIV injection disrupt your treatment. We help eligible patients access Cabenuva (cabotegravir and rilpivirine extended-release IM injections) for as little as $69.95 per month through the manufacturer’s Patient Assistance Program.
- Clear & Transparent Pricing
- Paperwork & Doctor-Coordination
- Comprehensive Support: From Application to Entire Journey
- Annual Re-certification And Refills Management
- Medicare Part D Patients Accepted
Key Takeaways:
- Cabenuva (cabotegravir + rilpivirine extended-release) is FDA-approved as a complete HIV-1 treatment regimen in adults and adolescents (12 years and older, at least 35 kg) who are virologically suppressed on a stable antiretroviral regimen. First long-acting injectable HIV treatment — IM injection every 1 or 2 months. Alternative to daily oral HIV regimens.
- Without assistance, Cabenuva costs commonly run approximately $40,000+ per year.
- Through AffordMyPrescriptions, qualifying patients can access Cabenuva for a flat $69.95 per month.
- Other HIV treatment regimens (all daily oral): Biktarvy (most-prescribed single-tablet regimen), Dovato (2-drug single tablet), Triumeq, Genvoya, Odefsey, Symtuza, and many generic regimens (Atripla generic, Complera generic, Symfi). Cabotegravir (Apretude — a Cabenuva component) is also used as long-acting HIV PrEP every 2 months. Sunlenca (lenacapavir SC every 6 months) for multidrug-resistant HIV. Ryan White HIV/AIDS Program funds HIV treatment; state ADAP.
What is Cabenuva Prescription Assistance Program?
The Cabenuva Patient Assistance Program helps eligible patients access this long-acting injectable HIV treatment at little or no cost when meeting income, insurance, and clinical criteria.
At AffordMyPrescriptions, our Patient Advocates handle the entire Cabenuva PAP enrollment for a flat $69.95 per month — so you never face a gap in Cabenuva HIV therapy.
AffordMyPrescriptions eliminates that burden. For a flat $69.95 per month, our Patient Advocates handle every step of your Cabenuva enrollment — so you never face a gap in your long-acting injectable HIV treatment.
Pharmacy Price Comparison
- Without assistance, Cabenuva costs thousands per month. A Patient Assistance Program can offset costs if you qualify:
| PHARMACY | PRICE (30-DAY) WITH BEST COUPONS | YOU SAVE W/ US |
|---|---|---|
| Ryan White HIV/AIDS Program | programs | State ADAP funding |
| Specialty pharmacy | ~$3,500/mo | Save substantially |
| HIV clinic | ~$3,700/mo | Save substantially |
| 340B-eligible institution | ~$2,900/mo | Save substantially |
| Biktarvy (alt oral daily) | ~$4,000/mo | Alt STR HIV therapy |
| Generic Atripla (alt) | ~$40/mo | Very cheap generic HIV STR |
*Retail prices are estimates based on public data and vary by pharmacy. Coupon prices from GoodRx and SingleCare as of April 2026. AffordMyPrescriptions Advocacy Service bypasses pharmacy pricing entirely by using the manufacturer’s assistance program to secure your Cabenuva — independent of dosage or retail price.
Our Pricing:
$69.95 Per month
1 Medications
$79.95 Per Month
2 Medications
$89.95 Per Month
3 Medications
$99.95 Per Month
4+ Medications
Why choose us For Your Cabenuva Prescription Program?
The Cabenuva Patient Assistance Program is free to apply. Our $69.95 per month covers full advocacy. Ryan White HIV/AIDS Program and state AIDS Drug Assistance Programs (ADAP) fund HIV treatment. Long-acting injectable HIV therapy addresses the adherence and stigma challenges of daily pills.
Enroll
Complete a simple eligibility form so our team can determine if you may qualify for Cabenuva assistance.
We Advocate
Our specialists gather documentation, complete applications, and coordinate with your prescriber and the assistance program.
Receive Medication
Once approved, your Cabenuva is delivered through the assistance program while we manage refills and annual renewals.
Discount Coupons vs. Patient Assistance Programs
Many patients try discount cards first. Here’s why the Patient Assistance Program through AffordMyPrescriptions is the better long-term solution for Cabenuva:
Limitations of Coupons
Prices fluctuate — savings aren’t guaranteed month-to-month
Copay accumulators may prevent savings from counting toward your deductible
Coupon cards expire and require constant renewal
Still $3,000–$3,700 per month even with the best discount
Cannot be used with Medicare, Medicaid, or government insurance
Advantages of PAP Through Us
Fixed $69.95/month — never changes regardless of retail price
- No expiration — continuous access as long as you qualify
Medication supplied directly through the assistance program
We manage all paperwork, refills, and annual renewals
Medicare Part D patients accepted
If denied, we explore alternative savings paths on your behalf
DO YOU QUALIFY?
Eligibility is generally determined by annual household income and insurance status. Most programs follow guidelines that include limits of up to $40,000 for individuals, $60,000 for couples, and $100,000 for larger families. Because requirements vary by program and household, we encourage you to contact AffordMyPrescriptions directly so we can review your specific situation and determine if you qualify for Cabenuva assistance.
- You Are A U.S. Citizen Or Legal Resident
- You Have A Valid Cabenuva Prescription From A Licensed U.S. Healthcare Provider
- You Are Uninsured, Underinsured, Or A Medicare Part D Beneficiary
- You Have Recently Experienced A Change In Financial Circumstances That Affects Your Ability To Pay
Understanding Cabenuva:
Cabenuva is the first long-acting injectable HIV-1 treatment — cabotegravir (INSTI) + rilpivirine (NNRTI) IM every 1 or 2 months. A complete HIV regimen for virologically suppressed patients that replaces daily oral therapy, addressing the adherence and stigma challenges of daily pill-taking.
How It Works:
HIV-1 treatment traditionally requires daily oral antiretroviral therapy. Adherence to daily pills can be challenging. Long-acting injectable HIV treatment reduces medical contact to monthly or every-2-month visits and eliminates daily pill-taking — for patients already virologically suppressed and appropriate for switch. Cabenuva combines cabotegravir (INSTI — blocking HIV integrase) and rilpivirine (NNRTI — blocking HIV reverse transcriptase). Both are long-acting depot IM injections. Every 1 month or every 2 months. Requires virologic suppression on a stable regimen before switch. ATLAS and FLAIR trials demonstrated non-inferiority to daily oral regimens for maintaining viral suppression.
Form and Use:
Cabenuva IM injection in the gluteus. Monthly regimen: cabotegravir 400 mg + rilpivirine 600 mg IM monthly. Every-2-month regimen: cabotegravir 600 mg + rilpivirine 900 mg IM every 2 months. Requires virologic suppression on stable ART before switch. May include an optional oral cabotegravir + rilpivirine lead-in for 4 weeks.
Generic Availability:
No generic Cabenuva. Other HIV treatment regimens (all daily oral): Biktarvy (bictegravir/emtricitabine/tenofovir alafenamide — most-prescribed single-tablet regimen), Dovato (dolutegravir/lamivudine — 2-drug single tablet), Triumeq, Genvoya, Odefsey, Symtuza. Generic oral HIV single-tablet regimens: Atripla generic, Complera generic, Symfi. Cabotegravir is also used as PrEP (Apretude every 2 months IM). Sunlenca (lenacapavir long-acting SC every 6 months) for multidrug-resistant HIV. Ryan White HIV/AIDS Program funds HIV treatment; state ADAP. HIV Medicine Association resources.
Warnings:
Hypersensitivity reactions (including DRESS — rare but serious; contraindicated with history of hypersensitivity to cabotegravir or rilpivirine), hepatotoxicity (monitor LFTs), depression and suicidality (monitor for mood changes — INSTI class; screen before starting), injection site reactions (very common — pain, swelling, nodules), long pharmacological tail (many months after last injection — implications for missed doses and resistance risk), drug interactions (rifamycins contraindicated; other CYP3A4 inducers reduce levels), embryo-fetal considerations. Other: pyrexia, fatigue, headache, musculoskeletal pain, nausea, rash. Discontinuation planning is important given the long pharmacological tail.
FAQ (Frequently Asked Questions)
How much does Cabenuva cost without insurance?
$40,000+ per year ($3,000–$3,700 per month). Comparable to brand daily oral HIV therapy (Biktarvy ~$4,000/month). Generic oral HIV single-tablet options (Atripla generic, Complera generic) are ~$40–$100/month — dramatically cheaper if daily pill adherence is acceptable.
How is Cabenuva different from daily oral HIV therapy?
Cabenuva is an IM injection every 1 or 2 months. Daily oral regimens (Biktarvy, Dovato, Triumeq, generic Atripla) require daily pill-taking. Cabenuva eliminates daily pills — addressing adherence challenges and pill-taking stigma. Requires virologic suppression on stable ART before switch.
Who is appropriate for Cabenuva?
Adults and adolescents (12+ years, at least 35 kg) with HIV-1 who are virologically suppressed on stable ART. Not for treatment-naive or virologically failing patients. Considerations include pregnancy, hepatitis B co-infection, and resistance history. Discuss with an HIV specialist.
How is Cabenuva different from Apretude?
Both contain long-acting cabotegravir IM injection. Apretude is cabotegravir alone for HIV PrEP (prevention). Cabenuva combines cabotegravir with rilpivirine for HIV treatment in virologically suppressed patients. Different indications and regimens.
What are Cabenuva side effects?
Injection site reactions (pain, swelling — very common), pyrexia, fatigue, headache, musculoskeletal pain, nausea, rash. Serious: hypersensitivity reactions (including DRESS — rare), hepatotoxicity, depression/suicidality (INSTI class), drug interactions. Long pharmacological tail has implications for discontinuation.
Take Control of Your Medication Costs
Long-acting injectable HIV treatment transforms adherence and quality of life. Our advocacy team is ready — $69.95 per month, or free if we cannot help.
Submit Enrollment Form
Start free by filling out a simple online form.
Receive Welcome Call
Our specialist will contact you for a quick welcome call.
We Manage The Process
Our team handles everything, so you can focus on your health.