AKEEGA Patient Assistance Program
Don’t let the high cost of brand combination tablet for BRCA-mutated metastatic castration-resistant prostate cancer disrupt your treatment. We help eligible patients access Akeega (niraparib + abiraterone acetate dual-action tablets) for as little as $69.95 per month through the manufacturer’s Patient Assistance Program.
- Clear & Transparent Pricing
- Paperwork & Doctor-Coordination
- Comprehensive Support: From Application to Entire Journey.
- Annual Re-certification And Refills Management
- Medicare Part D Patients Accepted
HIPAA Compliant
BBB Accredited
Secure Website
Key Takeaways:
- Akeega (niraparib + abiraterone acetate) is FDA-approved in combination with prednisone for adults with deleterious or suspected deleterious BRCA-mutated (germline or somatic) metastatic castration-resistant prostate cancer (mCRPC). First fixed-dose PARP inhibitor + androgen synthesis inhibitor dual-action tablet — simplifies pill burden vs separate components.
- Without assistance, Akeega costs commonly run approximately $14,000–$17,000 per month.
- Through AffordMyPrescriptions, qualifying patients can access Akeega for a flat $69.95 per month.
- Component generics partially available — generic abiraterone widely available very cheap (~$200/mo), but niraparib (Zejula) remains brand only. Other BRCA-mutated mCRPC options: Lynparza (olaparib — PARP, in combination with abiraterone), Talzenna (talazoparib + enzalutamide combination), Rubraca (rucaparib). Other mCRPC therapies: Xtandi (enzalutamide), Erleada (apalutamide), Nubeqa (darolutamide), Zytiga (abiraterone — generic), Pluvicto (lutetium-177-PSMA-617 for PSMA-positive), docetaxel/cabazitaxel chemo (generic), radium-223 (Xofigo) for bone-predominant disease. Tumor and germline genetic testing essential — BRCA testing is now standard of care in mCRPC.
What Is Akeega Prescription Assistance Program?
The Akeega Patient Assistance Program is a manufacturer-sponsored initiative that helps eligible patients access Akeega (used for BRCA-mutated metastatic castration-resistant prostate cancer in combination with prednisone) at little or no cost when they meet specific income, insurance, and clinical criteria. The program is free to apply for, but the enrollment process involves detailed applications, urology or medical oncology coordination, BRCA mutation documentation, supporting documentation, and ongoing renewal — which can be overwhelming when you are managing advanced prostate cancer.
At AffordMyPrescriptions, our Patient Advocates handle the entire Akeega PAP enrollment for a flat $69.95 per month. We complete the application, coordinate with your oncologist for required medical documentation (typically including BRCA testing results, prior treatment history, and clinical criteria), follow up with the manufacturer’s program until approval, manage your refills, and handle annual re-certification — so you never face a gap in your Akeega targeted therapy.
AffordMyPrescriptions eliminates that burden. For a flat $69.95 per month, our Patient Advocates handle every step of your Akeega enrollment — from the initial application through ongoing refills and annual re-enrollment — so you never face a gap in your metastatic prostate cancer treatment.
Pharmacy Price Comparison
- Without assistance, Akeega costs thousands of dollars per month at specialty pharmacies. Discount cards and pharmacy coupons offer minimal relief at this price point, but a Patient Assistance Program can make this targeted therapy accessible if you qualify. The table below compares typical retail pricing across major pharmacies to what you'd pay with our Akeega advocacy service:
| Pharmacy(With Coupon) | PrIce (30-Day)* | You Save W/ Us |
|---|---|---|
| Walgreens | ~$16,500/mo | Save substantially |
| CVS Pharmacy | ~$17,000/mo | Save substantially |
| Walmart | ~$14,500/mo | Save substantially |
| Generic abiraterone (component) | ~$200/mo | Generic component cheap |
| Lynparza + Zytiga generic (alt) | ~$14,500/mo | Alt PARP + AR combo |
*Retail prices are estimates based on public data and vary by pharmacy. Coupon prices from GoodRx and SingleCare as of April 2026. AffordMyPrescriptions Advocacy Service bypasses pharmacy pricing entirely by using the manufacturer’s assistance program to secure your Cialis — independent of dosage or retail price.
Our Pricing:
$69.95 Per month
1 Medications
$79.95 Per Month
2 Medications
$89.95 Per Month
3 Medications
$99.95 Per Month
4+ Medications
Why choose us For Your Akeega Prescription Program?
The Akeega Patient Assistance Program is free to apply and provides medication at no cost if approved. But the process involves detailed applications, prescriber coordination, documentation, and ongoing management — applications that are commonly delayed or denied when paperwork is incomplete. Our $69.95 per month covers full advocacy: applications, doctor coordination, documentation, refill management, and re-enrollment — so you focus on your health, not paperwork. BRCA testing is essential for Akeega candidacy — and generic abiraterone offers cheaper backbone when combined with brand PARP inhibitor.
Enroll
Complete a simple eligibility form so our team can determine if you may qualify for medication assistance programs.
We Advocate
Our specialists help gather documentation, complete applications, and coordinate with program providers.
Receive Medication
Once approved, you may receive your medication through the assistance program while we help manage ongoing paperwork and renewals.
Discount Coupons vs. Patient Assistance Programs
Many patients try discount cards first. Here’s why the Patient Assistance Program through AffordMyPrescriptions is the better long-term solution for Akeega:
Limitations of Coupons
- Prices fluctuate — savings aren’t guaranteed month-to-month
- Copay accumulators may prevent savings from counting toward deductible
- Coupon cards expire and require constant renewal
Still $400–$600 per month even with the best discount
- Can’t be used with Medicare, Medicaid, or government insurance
Advantages of PAP Through Us
- Fixed $69.95/month — never changes regardless of retail price
- No expiration — continuous access as long as you qualify
- Medication supplied directly from the manufacturer
We manage all paperwork, refills, and annual renewals
- If denied, we explore alternative savings on your behalf
DO YOU QUALIFY?
Eligibility is generally determined by annual household income and insurance status. Most programs follow guidelines that include limits of up to $40,000 for individuals, $60,000 for couples, and $100,000 for larger families. Because requirements vary by program and household, we encourage you to contact AffordMyPrescriptions directly so we can review your specific situation and determine if you qualify for Akeega assistance.
- You Are A U.S. Citizen Or Legal Resident
- You have a valid Cialis prescription from a licensed U.S. healthcare provider
- You Are Uninsured Or Underinsured And Cannot Afford Your Medication
- You have recently experienced a change in financial circumstances that affects your ability to pay
Not sure if you qualify? Our pre-qualification check is completely free. If we can’t help, you won’t be charged.
Understanding Akeega:
Akeega is the first FDA-approved fixed-dose combination of a PARP inhibitor (niraparib) and an androgen synthesis inhibitor (abiraterone acetate) for BRCA-mutated mCRPC. The combination exploits synthetic lethality in BRCA-deficient tumors while simultaneously suppressing androgen signaling — the dual mechanism produces improved outcomes vs abiraterone alone in BRCA-mutated disease per the MAGNITUDE trial.
How it works:
Metastatic castration-resistant prostate cancer (mCRPC) progresses despite testosterone suppression. Tumors with BRCA1/2 mutations have impaired homologous recombination DNA repair — synthetic lethality vulnerability to PARP inhibition. Combining PARP inhibition with androgen receptor pathway suppression targets two key drivers simultaneously.
Niraparib inhibits PARP — preventing repair of single-strand DNA breaks that become unrepaired double-strand breaks; BRCA-deficient tumors cannot repair these via homologous recombination, leading to cell death. Abiraterone inhibits CYP17A1 — blocking adrenal and intratumoral androgen synthesis. The combination demonstrated improved radiographic progression-free survival vs abiraterone alone in BRCA-mutated mCRPC (MAGNITUDE trial). Prednisone co-administration prevents mineralocorticoid excess from abiraterone.
Form and use:
Akeega tablets in two strengths (niraparib 100 mg / abiraterone 500 mg and niraparib 50 mg / abiraterone 500 mg). Recommended dose 2 tablets once daily (200 mg niraparib / 1000 mg abiraterone). Take on empty stomach (at least 1 hour before or 2 hours after food). Coadminister prednisone 10 mg daily. Continue until disease progression or unacceptable toxicity. Periodic CBC, comprehensive metabolic panel, blood pressure, and clinical assessment.
Generic availability:
No generic Akeega. Component generics: abiraterone (Zytiga generic — widely available, very cheap ~$150–$300/mo); niraparib (Zejula — brand only). Other BRCA-mutated mCRPC therapies: Lynparza (olaparib) + abiraterone combination per PROpel, Talzenna (talazoparib) + enzalutamide combination per TALAPRO-2 (HRR-mutated population), Rubraca (rucaparib) for BRCA-mutated mCRPC. Other mCRPC options: Xtandi (enzalutamide), Erleada (apalutamide), Nubeqa (darolutamide), Pluvicto (lutetium-177-PSMA-617 for PSMA-positive disease after ≥1 prior taxane and AR pathway inhibitor), Xofigo (radium-223 for bone-predominant disease), docetaxel and cabazitaxel chemotherapy (generic), sipuleucel-T (Provenge) for asymptomatic/minimally symptomatic. Continued androgen deprivation therapy (LHRH agonist or antagonist) backbone. Tumor and germline genetic testing (BRCA1/2 and broader HRR panel) is standard of care in mCRPC.
Warnings:
**Boxed and important warnings: myelodysplastic syndrome / acute myeloid leukemia (MDS/AML — rare but serious with PARP class, monitor CBC; evaluate persistent cytopenia patterns), severe hypertension and cardiovascular events (abiraterone — monitor BP, manage hypertension aggressively), hepatotoxicity (monitor LFTs especially first months), cytopenias (anemia, thrombocytopenia, neutropenia — common dose-limiting), hypokalemia and fluid retention (abiraterone mineralocorticoid excess — managed with prednisone co-administration).** Other: fatigue, nausea, decreased appetite, embryo-fetal toxicity (women of childbearing potential should not handle without protection), drug interactions (strong CYP3A4 inhibitors/inducers — significant interactions with niraparib and abiraterone), pneumonitis (rare). Use approved barrier methods during sexual activity per labeling.
FAQ (Frequently Asked Questions)
How much does Akeega cost without insurance?+
$14,000–$17,000 per month. Annual cost approaches $200,000 without assistance. Specialty pharmacy and Patient Assistance Programs are essential for most patients.
Why is BRCA testing required before starting Akeega?+
Akeega is FDA-approved specifically for BRCA1/2-mutated mCRPC. PARP inhibitors exploit synthetic lethality in BRCA-deficient tumors — patients without BRCA mutations are less likely to benefit. Germline testing (saliva or blood) plus tumor genetic testing is now standard in mCRPC to identify PARP inhibitor candidates and to inform family counseling. |
What is the difference between Akeega and taking generic abiraterone plus Zejula separately?+
Akeega combines both in one tablet — simpler dosing. Pharmacologically equivalent to taking generic abiraterone with brand niraparib but at fixed dose ratio. Cost considerations vary — some patients can access generic abiraterone (cheap) + brand niraparib (very expensive) separately, but Akeega’s fixed combination is the studied regimen in MAGNITUDE.Akeega combines both in one tablet — simpler dosing. Pharmacologically equivalent to taking generic abiraterone with brand niraparib but at fixed dose ratio. Cost considerations vary — some patients can access generic abiraterone (cheap) + brand niraparib (very expensive) separately, but Akeega’s fixed combination is the studied regimen in MAGNITUDE.
Why is prednisone required with Akeega?+
Abiraterone blocks CYP17A1 — but the resulting downstream feedback can cause mineralocorticoid excess (hypertension, fluid retention, hypokalemia). Low-dose prednisone 10 mg daily prevents this. Standard practice with all abiraterone regimens.
How serious are the FDA boxed warnings for Akeega?+
Significant. PARP class warning for MDS/AML — rare but life-threatening. Abiraterone component warnings for severe hypertension, hypokalemia, fluid retention, hepatotoxicity. Monitoring CBC, BP, electrolytes, and LFTs at baseline and periodically is essential.
Can I take Akeega with food?+
Strong CYP3A4 inhibitors (azoles, clarithromycin, ritonavir, grapefruit) and inducers (rifampin, phenytoin, carbamazepine, St. John’s wort) interact with both components. Abiraterone is also a CYP2D6 inhibitor — caution with substrates (e.g., metoprolol, dextromethorphan). Discuss all medications with your oncologist or pharmacist.
What happens if my Akeega Patient Assistance Program application is denied?+
We help explore separate generic abiraterone (very cheap component) plus Zejula or Lynparza copay programs, Lynparza + abiraterone combination per PROpel, Talzenna + enzalutamide per TALAPRO-2, alternative mCRPC therapies (Xtandi, Erleada, Nubeqa, Pluvicto, Xofigo, docetaxel/cabazitaxel), Leukemia & Lymphoma Society copay assistance, Patient Access Network, Patient Advocate Foundation, CancerCare, Prostate Cancer Foundation, Us TOO International, Medicare Part D Extra Help, and state SPAP programs.
Take Control of Your Medication Costs
Targeted therapy for BRCA-mutated metastatic prostate cancer should not be derailed by cost. Genetic testing and proper patient selection are essential. Our Akeega advocacy team is ready to verify your eligibility, complete the manufacturer application on your behalf, and manage your prescription through approval, delivery, and renewal — for a flat $69.95 per month. If we cannot help you access Akeega through a Patient Assistance Program, you are not charged. Call (833) 556-2729 or check your eligibility online today.
Submit Enrollment Form
Start free by filling out a simple online form.
Receive Welcome Call
Our specialist will contact you for a quick welcome call.
We Manage The Process
Our team handles everything, so you can focus on your health.