Genentech’s official Actemra Co-pay Program can reduce your out-of- pocket cost to $0 per treatment – up to $15,000 per calendar year – for eligible patients with commercial insurance.
Possible cost per treatment
Max savings per calendar year
Typical monthly cost without help
The official program name is the ACTEMRA Co-pay Program, run by Genentech (the maker of Actemra). It is a manufacturer-sponsored savings card designed to help commercially insured patients cover the cost of their insurance copay, co-insurance, or other out-of-pocket expenses for Actemra.
When you have private or commercial health insurance that covers Actemra, you still face a copay — often hundreds or thousands of dollars per infusion or injection. The Actemra Co-pay card works alongside your insurance to bring your share down to as little as $0 per treatment.
The program is run through RACopay.com, the official Genentech portal. You can register online or call (855) RA-COPAY (855-722-6729). Once enrolled, eligible patients receive a virtual debit card that covers their out-of-pocket cost at the point of care — whether at an infusion center or a specialty pharmacy.
The Actemra Co-pay Program has specific criteria. Make sure you review both the qualifying and disqualifying factors before applying.
If you fall into any of the “do not qualify” categories, a Patient Assistance Program (PAP) may be a better fit — especially if you are on Medicare or uninsured. Check PAP eligibility →
The process is straightforward. Most patients are enrolled within a few business days.
Confirm you have an active commercial insurance plan that covers Actemra and that you are not enrolled in any federal or state government program as your primary payer.
Complete the online registration form at RACopay.com (the official Genentech portal) or enroll by phone. Your doctor's office can also help you register. Have your insurance card and prescription information ready.
Once approved, you receive a virtual debit card loaded with your benefit. The card is accepted at specialty pharmacies and infusion centers where Actemra is dispensed.
At your infusion center or specialty pharmacy, your copay is applied against your card balance. Your out-of-pocket cost drops to as little as $0 per treatment. The program covers up to $15,000 per calendar year.
The program resets every January 1. Eligible patients who meet ongoing criteria may be automatically re-enrolled, but you should confirm your enrollment status at the start of each year.
Both programs save you money on Actemra — but they serve very different patient situations. Use this table to find your best fit.
| Factor | Actemra Copay Card (RA Copay Program) | Patient Assistance Program (via AffordMyPrescriptions) |
|---|---|---|
| Who It's For | Commercially (privately) insured patients | Uninsured, underinsured, or Medicare Part D patients |
| Medication Cost | As low as $0/treatment | $0 medication cost if approved |
| Annual Cap | Up to $15,000/calendar year | No annual drug-cost cap — continuous supply |
| Service Fee | None (free program from Genentech) | $69.95/month advocacy fee (AffordMyPrescriptions) |
| Medicare Patients | Not eligible | Medicare Part D accepted |
| Uninsured Patients | Not eligible | Eligible based on income |
| Paperwork & Renewals | Managed by patient/provider via RACopay.com | Fully managed by AffordMyPrescriptions team |
| Copay Accumulator Risk | Potential issue with some plans | Not applicable — medication supplied directly |
| Income Verification | Not required | Required — income-based eligibility |
| Biosimilar Support | Actemra brand only | Can help explore biosimilar PAPs too |
PAP through AffordMyPrescriptions: $69.95/month covers full advocacy, paperwork, refills, and re-certification. Medication itself is at no cost if approved.
If you have Medicare, are uninsured, or your income meets PAP guidelines, the Actemra Patient Assistance Program can deliver your medication at no drug cost. AffordMyPrescriptions handles the entire process — applications, doctor coordination, refills, and annual re-certification — for a flat $69.95/month. Medicare Part D patients are accepted.
Understanding your medication helps you make the most of available savings programs — and know which formulation your copay card applies to.
FDA-approved for moderately to severely active RA in adults with an inadequate response to one or more DMARDs. Available as IV infusion (every 4 weeks) or SC injection (weekly or every 2 weeks).
Approved for GCA in adults. Allows for rapid corticosteroid tapering and helps prevent disease flares. Subcutaneous 162 mg weekly injection is the approved form for GCA.
Approved for both systemic JIA (sJIA) and polyarticular JIA (pJIA) in patients 2 years and older. Note: for minor patients, a caregiver or legally authorized person must manage co-pay assistance.
Also approved for Cytokine Release Syndrome (CRS) from CAR-T therapy, COVID-19 in select hospitalized adults, and Systemic Sclerosis-Associated ILD (SSc-ILD).
Actemra IV: Weight-based dosing administered every 4 weeks at an infusion center for RA. Single doses for CRS and COVID-19.
Actemra SC: 162 mg subcutaneous injection given weekly (GCA) or weekly/every 2 weeks (RA). Can be self-administered at home after training.
FDA-approved tocilizumab biosimilars Tofidence and Tyenne are now available at substantially lower cost. If your prescriber switches you to a biosimilar, the Actemra copay card no longer applies — a separate biosimilar savings program may be available. Another IL-6 pathway option is sarilumab (Kevzara), given subcutaneously every 2 weeks with its own manufacturer savings program.
Actemra is a high-cost specialty biologic. Without assistance, most patients face significant out-of-pocket expenses even with insurance.
| Pharmacy / Setting | Retail Price (30-Day) | With Copay Card (eligible patients) | With AffordMyPrescriptions PAP |
|---|---|---|---|
| Walgreens | ~$5,200 | As low as $0 | $0 drug cost + $69.95 fee |
| CVS Pharmacy | ~$5,500 | As low as $0 | $0 drug cost + $69.95 fee |
| Walmart | ~$3,800 | As low as $0 | $0 drug cost + $69.95 fee |
| Biosimilar (Tofidence/Tyenne) |
~$2,500 | Separate biosimilar card required | Biosimilar PAP may apply |
Retail prices are estimates based on publicly available data and vary by pharmacy, dose, and insurance. Copay card savings depend on your insurance plan and the $15,000/year program cap.
Several situations can limit or eliminate your copay card benefit. Here’s what to explore for each scenario.
Once you exhaust the annual benefit, you owe your full copay for the rest of the year. Options: contact foundations like the Arthritis Foundation, PAN Foundation, or HealthWell Foundation for bridge assistance.
Copay accumulator programs prevent the card from counting toward your deductible, meaning a large bill arrives mid-year. Review your EOB and plan documents early, or switch to a plan without accumulators at open enrollment.
The copay card is not available to you. A Patient Assistance Program is the main path to accessing Actemra affordably. Income-based eligibility applies. Medicare Part D beneficiaries are commonly accepted.
Our Patient Assistance Program advocacy service is designed for exactly these situations — Medicare patients, the uninsured, or anyone the copay card can’t fully protect. For a flat $69.95/month, we handle everything so you can focus on your health.
Still have questions? Here are the answers patients ask most often about the Actemra Co-pay Program.
Register online at RACopay.com or call (855) RA-COPAY (855-722-6729). You can also ask your doctor’s office or infusion center to help with enrollment. Have your insurance information and prescription details ready. Once approved, you’ll receive a virtual debit card.
The program provides up to $15,000 in assistance per calendar year. For eligible patients, this means your out-of-pocket cost can be as little as $0 per treatment. However, once this limit is reached, you are responsible for your full copay for the remainder of the year. The limit resets every January 1.
Yes. The Actemra Co-pay Program covers both the intravenous (IV) infusion and the subcutaneous (SC) injection formulations, provided you are using brand-name Actemra and meet the other eligibility requirements. The virtual debit card works at both infusion centers and specialty pharmacies.
If your plan uses a copay accumulator or copay maximizer program, payments made by the Actemra copay card will not count toward your deductible or out-of-pocket maximum. This can result in you facing a large bill later in the plan year once the card funds are exhausted. Review your plan’s Summary of Benefits and Coverage (SBC) or call your insurer to confirm how your plan treats manufacturer copay card payments before you rely on it as your primary savings strategy.
No. The Actemra Co-pay Program covers brand-name Actemra only. If your prescriber switches you to a biosimilar such as Tofidence or Tyenne, you would need to enroll in the biosimilar manufacturer’s own savings program, which is a separate card or assistance program.
No. The Actemra Co-pay Program covers drug costs only. Infusion center administration fees, facility charges, and nursing fees are billed separately through your insurance and are not covered by this program. You may still owe a facility copay even if your drug cost is $0.
Yes, but not through the copay card — it requires active commercial insurance. Uninsured patients may qualify for Genentech’s Patient Assistance Program, which can provide Actemra at no medication cost based on income. AffordMyPrescriptions can help you navigate this process. Use the link below to check your eligibility for free.
If you have commercial insurance, the Actemra Co-pay Program is a great first step — apply at RACopay.com. If you’re on Medicare, uninsured, or the copay card alone isn’t enough, our Patient Assistance Program advocacy service may help you access Actemra at no drug cost for a flat $69.95/month.