VIBERZI (eluxadoline) Patient Assistance Program

Don’t let the high cost of brand IBS-D therapy disrupt your treatment. We help eligible patients access Viberzi (eluxadoline) for as little as $69.95 per month through the manufacturer’s Patient Assistance Program.

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Key ​Takeaways:

What Is Viberzi Prescription Assistance Program?

Viberzi PAP for IBS-D patients.

Eligibility, GI coordination.

AffordMyPrescriptions eliminates that burden. $69.95/month advocacy.

Pharmacy Price Comparison

Pharmacy(With Coupon)PrIce (30-Day)*You Save W/ Us
Walgreens

~$1,450

Save ~$1,380/mo

CVS Pharmacy

~$1,500

Save ~$1,430/mo

Walmart 

~$1,080

Save ~$1,010/mo

Costco

~$1,050

Save ~$980/mo

Generic loperamide

~$15

Already low (alt)

*Just a heads-up — retail prices are estimates based on public data and vary by pharmacy. AffordMyPrescriptions Advocacy Service bypasses this by using drug manufacturer programs to secure your medication directly at no cost or retail price.

Our Pricing:

$69.95 Per month

1 Medications

$79.95 Per Month

2 Medications

$89.95 Per Month

3 Medications

$99.95 Per Month

4+ Medications

Why choose us For Your Viberzi Prescription Program?

Many patients try discount cards first. Here’s why the Patient Assistance Program through AffordMyPrescriptions is the better long-term solution for Viberzi:

Enroll

Complete a simple eligibility form so our team can determine if you may qualify for medication assistance programs.

We Advocate

Our specialists help gather documentation, complete applications, and coordinate with program providers.

Receive Medication

Once approved, you may receive your medication through the assistance program while we help manage ongoing paperwork and renewals.

Discount Coupons vs. Patient Assistance Programs

PAP at no cost. Generic IBS-D therapies (loperamide, amitriptyline, dicyclomine, cholestyramine) much cheaper alternatives for many patients.

Limitations of Coupons

  • Prices fluctuate — savings aren’t guaranteed month-to-month
  • Copay accumulators may prevent savings from counting toward deductible
  • Coupon cards expire and require constant renewal
  • Still $1,000–$1,500 per month even with the best discount

  • Can’t be used with Medicare, Medicaid, or government insurance

Advantages of PAP Through Us

  • Fixed $69.95/month — never changes regardless of retail price
  • No expiration — continuous access as long as you qualify
  • Medication supplied directly through the assistance program
  • We manage all paperwork, refills, and annual renewals
  • If denied, we explore alternative savings on your behalf

DO YOU QUALIFY?

Eligibility is generally determined by annual household income and insurance status. Most programs follow guidelines that include limits of up to $40,000 for individuals, $60,000 for couples, and $100,000 for larger families. Because requirements vary by program and household, we encourage you to contact AffordMyPrescriptions directly so we can review your specific situation and determine if you qualify for Viberzi assistance.

Not sure if you qualify?  Our pre-qualification check is completely free. If we can’t help, you won’t be charged.

Understanding Viberzi:

Viberzi is an oral mixed opioid receptor modulator for IBS-D. Mu-agonist/delta-antagonist/kappa-agonist activity in enteric nervous system reduces gut motility, secretion, and visceral pain — without significant CNS opioid effects (poor CNS penetration).

How Viberzi Works:

IBS-D involves disordered gut motility, secretion, and visceral hypersensitivity. Enteric opioid receptors regulate these functions.

Eluxadoline acts peripherally on enteric mu, delta, and kappa opioid receptors. Mu-agonism reduces motility (slows transit, reduces diarrhea); delta-antagonism may reduce constipation risk seen with pure mu-agonists; kappa-agonism reduces visceral pain. Minimal CNS penetration limits central opioid effects (no euphoria, addiction concerns). Effective for IBS-D abdominal pain and stool consistency.

Form and use:

Viberzi 100 mg twice daily by mouth, with food. Lower dose (75 mg BID) for patients who can’t tolerate higher dose or with certain contraindications. CONTRAINDICATED in patients without gallbladder (post-cholecystectomy) due to increased pancreatitis risk.

Generic availability:

No generic Viberzi. Other IBS-D therapies: rifaximin (Xifaxan generic available — antibiotic with role in IBS-D), alosetron (Lotronex generic — REMS-restricted to women with severe IBS-D), loperamide (generic, OTC, very cheap — diarrhea control only), bile acid sequestrants (cholestyramine, colesevelam — for bile acid diarrhea), TCAs (amitriptyline, nortriptyline generic), antispasmodics (dicyclomine, hyoscyamine generic), low-dose rifaximin for SIBO overlap.

Viberzi CONTRAINDICATED in: patients without gallbladder (severely increased pancreatitis risk — boxed warning), known/suspected biliary duct obstruction, alcoholism/alcohol abuse, history of pancreatitis, severe hepatic impairment, severe constipation. Other warnings: sphincter of Oddi spasm, pancreatitis (acute pancreatitis can occur in patients with intact gallbladder), CNS effects (somnolence, fatigue, dizziness).

Warnings:

Viberzi CONTRAINDICATED in: patients without gallbladder (severely increased pancreatitis risk — boxed warning), known/suspected biliary duct obstruction, alcoholism/alcohol abuse, history of pancreatitis, severe hepatic impairment, severe constipation. Other warnings: sphincter of Oddi spasm, pancreatitis (acute pancreatitis can occur in patients with intact gallbladder), CNS effects (somnolence, fatigue, dizziness).

FAQ (Frequently Asked Questions)

Cost ?

$1,000–$1,500/month. PAP at no cost. Generic IBS-D alternatives much cheaper.

CONTRAINDICATED — Viberzi after cholecystectomy carries severely increased risk of severe pancreatitis, including fatal cases. Boxed warning. Discuss alternatives with GI specialist.

Often yes. Loperamide (OTC, very cheap) for diarrhea control. Amitriptyline or nortriptyline (generic) for IBS pain and slowing motility. Dicyclomine (generic) for cramping. Cholestyramine if bile acid diarrhea. Insurance often requires trial of these before approving Viberzi.

Antibiotic with role in IBS-D and SIBO. Generic now available. 14-day course can provide weeks-to-months of relief in some IBS-D patients. Alternative to Viberzi for many.

Boxed warning — increased pancreatitis risk especially in patients without gallbladder. Also higher risk with alcohol abuse, prior pancreatitis. Severe abdominal pain, vomiting, fever should be evaluated promptly.

Evidence-based dietary intervention for IBS — reduces fermentable carbohydrates that exacerbate IBS symptoms. No drug cost. May be tried before/with medications.

Generic alternatives (loperamide, amitriptyline, dicyclomine, cholestyramine, rifaximin generic). Low FODMAP diet. Manufacturer copay program.

Take Control of Your Medication Costs

If struggling with Viberzi cost, we can help — or guide to generic IBS-D alternatives. Check eligibility today.

Submit Enrollment Form

Start free by filling out a simple online form.

Receive Welcome Call

Our specialist will contact you for a quick welcome call.

We Manage The Process

Our team handles everything, so you can focus on your health.

Receive Welcome Call

We Manage The Process