Don’t let the high cost of brand oral CGRP receptor antagonist acute migraine therapy disrupt your treatment. We help eligible patients access Ubrelvy (ubrogepant) for as little as $69.95 per month through the manufacturer’s Patient Assistance Program.
Ubrelvy PAP for migraine patients.
Eligibility, neurology/primary care coordination.
AffordMyPrescriptions eliminates that burden. $69.95/month advocacy.
| Pharmacy(With Coupon) | PrIce (30-Day)* | You Save W/ Us |
|---|---|---|
| Walgreens | ~$1,150 | Save ~$1,080/mo |
| CVS Pharmacy | ~$1,200 | Save ~$1,130/mo |
| Walmart | ~$990 | Save ~$2,180/mo |
| Costco | ~$2,220.00 | Save ~$2,150/mo |
Kroger | ~$2,250.00 | Save ~$2,180/mo |
*Just a heads-up — retail prices are estimates based on public data and vary by pharmacy. AffordMyPrescriptions Advocacy Service bypasses this by using drug manufacturer programs to secure your medication directly at no cost or retail price.
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The Patient Assistance Program is free to apply for and provides Tivicay at no medication cost if approved. Our $69.95/month service covers full advocacy.
Complete a simple eligibility form so our team can determine if you may qualify for medication assistance programs.
Our specialists help gather documentation, complete applications, and coordinate with program providers.
Once approved, you may receive your medication through the assistance program while we help manage ongoing paperwork and renewals.
Many patients try discount cards first. Here’s why the Patient Assistance Program through AffordMyPrescriptions is the better long-term solution for Tivicay:
Still $2,200–$2,500 per month even with the best discount
Eligibility is generally determined by annual household income and insurance status. Most programs follow guidelines that include limits of up to $40,000 for individuals, $60,000 for couples, and $100,000 for larger families. Because requirements vary by program and household, we encourage you to contact AffordMyPrescriptions directly so we can review your specific situation and determine if you qualify for Tivicay assistance.
Not sure if you qualify? Our pre-qualification check is completely free. If we can’t help, you won’t be charged.
Tivicay (dolutegravir, DTG) is a once-daily integrase strand transfer inhibitor (INSTI) used as a component of HIV-1 antiretroviral therapy. It must be combined with other antiretrovirals (NRTI backbone, or rilpivirine in the case of suppressed adults). Dolutegravir has a particularly high genetic barrier to resistance.
How Tivicay Works:
HIV-1 replication requires integrase — a viral enzyme that splices the HIV DNA copy into the host cell’s chromosomes. Without integration, HIV cannot establish persistent infection. INSTIs block this critical step.
Dolutegravir binds HIV integrase at the active site and prevents strand transfer — blocking integration of viral DNA into the host genome. Dolutegravir has a particularly high genetic barrier to resistance, meaning HIV needs to accumulate multiple mutations before becoming resistant — this makes dolutegravir-based regimens more forgiving of occasional missed doses than older HIV drugs.
Form and use:
Tivicay is taken by mouth once daily (or twice daily in patients with INSTI resistance). Available as 10, 25, and 50 mg tablets. Tivicay PD is a 5 mg dispersible tablet for pediatric dosing. Can be taken with or without food. Avoid taking with calcium, iron, magnesium, or aluminum supplements within 2 hours before or 6 hours after.
Generic availability:
There is no generic Tivicay in the U.S. as of 2026. Dolutegravir is also available in fixed-dose combinations: Dovato (DTG/3TC), Triumeq (DTG/ABC/3TC), and Juluca (DTG/RPV). The combination tablets simplify dosing for patients who are also taking other ARVs. HIV guidelines recommend INSTI-based regimens as first-line therapy.
Warnings:
Tivicay carries warnings for hypersensitivity reactions including DRESS (drug reaction with eosinophilia and systemic symptoms), hepatotoxicity (especially with HBV/HCV co-infection), depression/suicidality (rare), immune reconstitution syndrome, embryo-fetal toxicity (initial concern about neural tube defects from preliminary Botswana data, mostly reassured by larger subsequent studies), and weight gain (a class effect with INSTIs). Significant drug interactions occur with polyvalent cations, rifampin, rifabutin, certain antiepileptics, and St. John’s wort.
$950–$1,200/pack. PAP at no cost; advocacy $69.95/month. Generic triptans much cheaper if not contraindicated.
For patients without cardiovascular contraindications, generic triptans are first-line (dramatically cheaper, similar efficacy). For patients with CAD, stroke history, peripheral vascular disease, or uncontrolled hypertension, gepants are preferred (no vasoconstriction).
Both are oral gepants. Ubrelvy approved for acute migraine only. Nurtec ODT approved for both acute AND preventive — versatile if you need both functions.
Strong CYP3A4 inhibitors (ketoconazole, itraconazole, clarithromycin, ritonavir) contraindicated. Moderate inhibitors (fluconazole, diltiazem, erythromycin, verapamil) require dose adjustment. Tell prescriber about all medications.
Limited safety data. Discuss with neurologist.
Generic triptan if not contraindicated. NHF or Migraine Foundation may help.
If struggling with Ubrelvy cost, we can help — or consider generic triptan first-line. Check eligibility today.
Start free by filling out a simple online form.
Our specialist will contact you for a quick welcome call.
Our team handles everything, so you can focus on your health.