DELSTRIGO (doravirine/lamivudine) Patient Assistance Program
Don’t let the high cost of brand single-tablet HIV regimens disrupt your treatment. We help eligible patients access Delstrigo (doravirine/lamivudine/tenofovir disoproxil fumarate) for as little as $69.95 per month through the manufacturer’s Patient Assistance Program.
- Clear & Transparent Pricing
- Paperwork & Doctor-Coordination
- Comprehensive Support: From Application to Entire Journey.
- Annual Re-certification And Refills Management
- Medicare Part D Patients Accepted
HIPAA Compliant
BBB Accredited
Secure Website
Key Takeaways:
- Delstrigo (doravirine/lamivudine/tenofovir disoproxil fumarate, DOR/3TC/TDF) is a once-daily, single-tablet, complete HIV-1 regimen FDA-approved for treatment-naïve adults and pediatric patients (≥35 kg) with no known resistance to any of its components.
- Without assistance, Delstrigo costs commonly run approximately $3,200–$3,700 per 30-day supply.
- Through AffordMyPrescriptions, qualifying patients can access Delstrigo for a flat $69.95 per month — our advocacy team manages the entire enrollment, refills, and renewal process.
- There is no generic Delstrigo in the U.S. as of 2026. HIV guidelines generally prefer integrase-inhibitor-based regimens (Biktarvy, dolutegravir-based) for treatment-naïve patients. Delstrigo's NNRTI-based composition makes it a useful alternative for patients with INSTI intolerance.
What Is Delstrigo Prescription Assistance Program?
The Delstrigo Prescription Assistance Program is a manufacturer-sponsored initiative that provides Delstrigo at little or no medication cost to qualifying patients based on income and insurance status. The program is designed for HIV treatment patients who are uninsured or underinsured, as well as Medicare Part D beneficiaries.
Navigating the program on your own means dealing with eligibility verification, HIV provider coordination, prior-authorization documentation, and renewal deadlines.
AffordMyPrescriptions eliminates that burden. For a flat $69.95 per month, our Patient Advocates handle every step of your enrollment, from initial application through ongoing refill coordination and annual re-certification.
Pharmacy Price Comparison
- Without assistance, Delstrigo costs roughly $3,200–$3,700/month. A Patient Assistance Program is the meaningful path forward — if you qualify:
| Pharmacy(With Coupon) | PrIce (30-Day)* | You Save W/ Us |
|---|---|---|
| Walgreens | ~$3,600.00 | Save ~$3,530/mo |
| CVS Pharmacy | ~$3,700.00 | Save ~$3,630/mo |
| Walmart | ~$3,300.00 | Save ~$3,230/mo |
| Costco | ~$3,250.00 | Save ~$3,180/mo |
Kroger | ~$3,300.00 | Save ~$3,230/mo |
*Just a heads-up — retail prices are estimates based on public data and vary by pharmacy. AffordMyPrescriptions Advocacy Service bypasses this by using drug manufacturer programs to secure your medication directly at no cost or retail price.
Our Pricing:
$69.95 Per month
1 Medications
$79.95 Per Month
2 Medications
$89.95 Per Month
3 Medications
$99.95 Per Month
4+ Medications
Why choose us For Your Delstrigo Prescription Program?
The Patient Assistance Program is free to apply for and provides Delstrigo at no medication cost if approved. Our $69.95/month service covers full advocacy.
Enroll
Complete a simple eligibility form so our team can determine if you may qualify for medication assistance programs.
We Advocate
Our specialists help gather documentation, complete applications, and coordinate with program providers.
Receive Medication
Once approved, you may receive your medication through the assistance program while we help manage ongoing paperwork and renewals.
Discount Coupons vs. Patient Assistance Programs
Many patients try discount cards first. Here’s why the Patient Assistance Program through AffordMyPrescriptions is the better long-term solution for Delstrigo:
Limitations of Coupons
- Prices fluctuate — savings aren’t guaranteed month-to-month
- Copay accumulators may prevent savings from counting toward deductible
- Coupon cards expire and require constant renewal
Still $3,200–$3,700 per month even with the best discount
- Can’t be used with Medicare, Medicaid, or government insurance
Advantages of PAP Through Us
- Fixed $69.95/month — never changes regardless of retail price
- No expiration — continuous access as long as you qualify
- Medication supplied directly through the assistance program
- We manage all paperwork, refills, and annual renewals
- If denied, we explore alternative savings on your behalf
DO YOU QUALIFY?
Eligibility is generally determined by annual household income and insurance status. Most programs follow guidelines that include limits of up to $40,000 for individuals, $60,000 for couples, and $100,000 for larger families. Because requirements vary by program and household, we encourage you to contact AffordMyPrescriptions directly so we can review your specific situation and determine if you qualify for Delstrigo assistance.
- You Are A U.S. Citizen Or Legal Resident
- You Have A Valid Delstrigo Prescription From A Licensed U.S. Healthcare Provider
- You Are Uninsured, Underinsured, Or A Medicare Part D Beneficiary
- You Have Recently Experienced A Change In Financial Circumstances That Affects Your Ability To Pay
Not sure if you qualify? Our pre-qualification check is completely free. If we can’t help, you won’t be charged.
Understanding Delstrigo :
Delstrigo (DOR/3TC/TDF) is a once-daily, single-tablet, three-drug HIV-1 regimen combining the NNRTI doravirine with the NRTI backbone of lamivudine and tenofovir disoproxil fumarate (TDF).
How Delstrigo Works:
HIV-1 replication requires reverse transcriptase to convert viral RNA into DNA. Delstrigo attacks reverse transcriptase from two complementary directions.
Doravirine is an NNRTI — it binds reverse transcriptase at a non-active (allosteric) site, distorting the enzyme. Lamivudine and tenofovir are NRTIs — they get incorporated into the growing viral DNA chain and terminate elongation. Together, this three-drug combination achieves effective viral suppression. Delstrigo uses tenofovir disoproxil fumarate (TDF) — older than TAF but with similar antiviral activity (with slightly higher kidney and bone exposure).
Form and use:
Delstrigo is taken as one tablet by mouth once daily, with or without food. It is a complete regimen — no other antiretrovirals are needed. Unlike rilpivirine-based regimens, Delstrigo does not require a meal and does not interact with acid-reducing medications.
Generic availability:
There is no generic Delstrigo in the U.S. as of 2026. Doravirine is also available alone (Pifeltro) for combining with different NRTIs. Other complete single-tablet regimens include Biktarvy (BIC/FTC/TAF), Genvoya (EVG/c/FTC/TAF), Triumeq (DTG/ABC/3TC), Dovato (DTG/3TC, two-drug), and Symtuza (DRV/c/FTC/TAF). HIV guidelines generally prefer integrase-inhibitor-based regimens for treatment-naïve patients.
Warnings:
Delstrigo carries a BOXED WARNING for severe acute HBV exacerbation if discontinued in patients with HBV co-infection — HBV testing is required before starting. Other warnings include lactic acidosis/severe hepatomegaly with steatosis, new-onset or worsening renal impairment (TDF is more nephrotoxic than TAF), decreased bone mineral density (TDF), hepatotoxicity, depression/suicidality (rare), and immune reconstitution syndrome. Significant drug interactions: rifampin and other strong CYP3A inducers substantially reduce doravirine levels; anticonvulsants and St. John’s wort also reduce doravirine.
FAQ (Frequently Asked Questions)
How Much Does Delstrigo Cost Without Insurance?
Delstrigo costs approximately $3,200–$3,700 per 30-day supply. Through AffordMyPrescriptions, qualifying patients receive Delstrigo at no medication cost — our $69.95 monthly fee covers full advocacy and program management.
How Is Delstrigo Different From Biktarvy?
Both are once-daily, single-tablet, complete HIV regimens. Delstrigo is NNRTI-based (doravirine + 3TC + TDF). Biktarvy is INSTI-based (bictegravir + FTC + TAF). Biktarvy has a higher genetic resistance barrier and contains TAF instead of TDF (less kidney/bone exposure) — and is generally first-line in current guidelines. Delstrigo is useful for patients with INSTI intolerance or in resistance situations.
Why Does Delstrigo Use TDF Instead Of TAF?
Delstrigo combines doravirine with the established TDF-based NRTI backbone. TDF has been widely used for many years and is effective, though it has slightly higher rates of kidney and bone effects than the newer TAF formulation. The decision between TDF and TAF often comes down to baseline kidney function, age, and bone health considerations.
Are There Drug Interactions I Should Know About?
Yes. Rifampin substantially reduces doravirine levels (avoid). Rifabutin requires the doravirine dose to be increased to twice daily. Anticonvulsants (carbamazepine, phenytoin, phenobarbital) and St. John’s wort reduce doravirine. Unlike rilpivirine-based regimens, Delstrigo does NOT interact significantly with PPIs, H2 blockers, or antacids — a practical advantage.
What If I Have Hepatitis B Co-infection?
Delstrigo’s lamivudine and tenofovir both have activity against HBV. Tell your prescriber if you have HBV co-infection — you should not stop Delstrigo without HBV monitoring, as severe HBV flares can occur. HBV testing is required before starting.
Can I Get Delstrigo Through The PAP If I Have Medicare?
Yes. Medicare Part D beneficiaries can typically qualify, especially if you face specialty-tier copays. State ADAP programs may also coordinate with Medicare for HIV-treatment patients.
What If My Application Is Denied?
If denied, we explore alternatives — switching to an INSTI-based regimen with its own PAP (Biktarvy, Triumeq, Dovato), or Pifeltro + generic FTC/TDF, state ADAP, the manufacturer’s copay program for commercially insured patients, or independent foundations. If we cannot find a path, you won’t be charged our service fee.
Take Control of Your Medication Costs
If you are struggling with the high cost of Delstrigo, our team may be able to help you access assistance programs designed to make brand single-tablet HIV regimens affordable. Check your eligibility today.
Submit Enrollment Form
Start free by filling out a simple online form.
Receive Welcome Call
Our specialist will contact you for a quick welcome call.
We Manage The Process
Our team handles everything, so you can focus on your health.