We help eligible patients access Creon (pancrelipase) for the treatment of exocrine pancreatic insufficiency for as little as $69.95 per month through manufacturer Patient Assistance Programs.
The Creon Prescription Assistance Program provides up to 12 months of Creon at no medication cost to qualifying patients, with the option to reapply. For commercially insured CF patients, a dedicated savings program reduces costs to $0. For non-CF patients, a savings card reduces costs to $5/month ($3,000/year max).
AffordMyPrescriptions ensures the digestive enzymes your body needs are never out of reach. For a flat $69.95 per month, our Patient Advocates manage your enrollment, determine the right savings program for your specific EPI cause, and coordinate your high-volume refill schedule.
| Pharmacy(With Coupon) | PrIce (30-Day)* | You Save W/ Us |
|---|---|---|
| Walgreens | ~$226 | Save ~$156/mo |
| CVS Pharmacy | ~$135 | Save ~$65/mo |
| Walmart | ~$438 | Save ~$368/mo |
| Costco | ~$437 | Save ~$367/mo |
*Just a heads-up — retail prices are estimates based on public data and vary by pharmacy. AffordMyPrescriptions Advocacy Service bypasses this by using drug manufacturer programs to secure your medication directly at no cost or retail price.
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The Patient Assistance Program is free to apply and provides medication at no cost if approved. But the process involves detailed applications, prescriber coordination, documentation, and ongoing management. Our $69.95/month covers full advocacy: applications, doctor coordination, documentation, refill management, and re-enrollment — so you focus on your health, not paperwork.
Complete a simple eligibility form so our team can determine if you may qualify for medication assistance programs.
Our specialists help gather documentation, complete applications, and coordinate with program providers.
Once approved, you may receive your medication through the assistance program while we help manage ongoing paperwork and renewals.
Many patients try discount cards first. Here’s why the Patient Assistance Program through Afford My Prescriptions is the better long–term solution:
Eligibility is generally determined by annual household income levels. Most programs follow guidelines that include a limit of up to $40,000 for individuals, $60,000 for couples, and $100,000 for larger families. Because requirements can vary, we encourage you to contact AffordMyPrescriptions directly so we can review your specific situation.
Creon (pancrelipase) is a prescription pancreatic enzyme replacement therapy for exocrine pancreatic insufficiency (EPI) due to cystic fibrosis, chronic pancreatitis, pancreatectomy, or other conditions. It contains three digestive enzymes derived from porcine pancreas: lipase (digests fats), protease (digests proteins), and amylase (digests carbohydrates).
How It Works:
Each delayed-release capsule contains enzyme-containing microspheres with a protective coating. The coating shields enzymes from stomach acid. In the small intestine, the coating dissolves, releasing lipase, protease, and amylase to break down fats, proteins, and carbohydrates — just as your pancreas would if functioning normally.
Form and Use:
Available in 3,000 to 36,000 lipase unit strengths. Taken with every meal (3–6 capsules) and snack (1–2 capsules). Swallow whole with liquid. For patients who cannot swallow, capsules can be opened and microspheres sprinkled onto acidic soft food like applesauce.
Generic Availability:
No generic Creon is available. Other brand-name pancrelipase products (Zenpep, Pancreaze, Pertzye) exist but are distinct formulations, not generic equivalents. Switching brands should only be done under medical supervision.
Warnings:
Not safe for patients with pork allergies (derived from porcine pancreas). Do not chew capsule contents. Do not change dose without consulting your healthcare provider.
Creon costs $135–$1,705 per 100 capsules depending on strength. Monthly costs often reach $400–$1,200+. The CF savings program offers $0/month. The non-CF card offers $5/month. Through AffordMyPrescriptions, qualifying patients receive Creon at no cost for $69.95/month.
Dosing is individualized. Adults typically take 2–4 capsules of higher strengths per meal and 1–2 per snack. Your doctor adjusts based on symptoms and nutritional status.
Yes. You must take Creon with every meal and snack containing fat, protein, or carbohydrates. The enzymes cannot be stored in the body.
No. Creon is derived from porcine (pig) pancreas. All currently FDA-approved pancreatic enzyme products are porcine-derived.
No generic Creon is available. Zenpep, Pancreaze, and Pertzye are alternative brand-name products with different formulations and pricing.
If you are struggling with the high cost of Creon, our team may be able to help you access
assistance programs designed to make medications more affordable. Check your eligibility today and take the first step toward reducing your prescription costs.
Start free by filling out a simple online form.
Our specialist will contact you for a quick welcome call.
Our team handles everything, so you can focus on your health.