Invokamet (canagliflozin/metformin) Patient Assistance Program
Don’t let the high cost of brand SGLT2 inhibitor + metformin combination disrupt your type 2 diabetes treatment. We help eligible patients access Invokamet (canagliflozin/metformin tablets) for as little as $69.95 per month through the manufacturer’s Patient Assistance Program.
- Clear & Transparent Pricing
- Paperwork & Doctor-Coordination
- Comprehensive Support: From Application to Entire Journey
- Annual Re-certification And Refills Management
- Medicare Part D Patients Accepted
Key Takeaways:
- Invokamet (canagliflozin/metformin) is FDA-approved for treatment of type 2 diabetes in adults — combining an SGLT2 inhibitor (canagliflozin/Invokana) with metformin in a single tablet. Simplifies polypharmacy for diabetes patients. Canagliflozin also has cardiovascular and renal protection benefits demonstrated in trials.
- Without assistance, Invokamet costs commonly run approximately $600–$800 per month.
- Through AffordMyPrescriptions, qualifying patients can access Invokamet for a flat $69.95 per month.
- Other SGLT2 inhibitors: dapagliflozin (Farxiga; Xigduo XR is dapa+metformin combo), empagliflozin (Jardiance; Synjardy is empa+metformin; Trijardy XR is empa+linagliptin+metformin), ertugliflozin (Steglatro; Segluromet is ertu+metformin), Invokana (canagliflozin alone). Metformin (generic — very cheap first-line T2DM foundation). Combination pills improve adherence. Diabetes management also includes GLP-1s (Ozempic, Trulicity, Rybelsus, Mounjaro/Zepbound tirzepatide), DPP-4 inhibitors, insulins, sulfonylureas (generic), pioglitazone (generic).
What is Invokamet Prescription Assistance Program?
The Invokamet Patient Assistance Program helps eligible patients access this SGLT2 inhibitor/metformin combination at little or no cost when meeting income, insurance, and clinical criteria.
At AffordMyPrescriptions, our Patient Advocates handle the entire Invokamet PAP enrollment for a flat $69.95 per month — so you never face a gap in Invokamet therapy.
AffordMyPrescriptions eliminates that burden. For a flat $69.95 per month, our Patient Advocates handle every step of your Invokamet enrollment — so you never face a gap in your type 2 diabetes treatment.
Pharmacy Price Comparison
- Without assistance, Invokamet costs hundreds per month. A Patient Assistance Program can offset costs if you qualify:
| PHARMACY | PRICE (30-DAY) WITH BEST COUPONS | YOU SAVE W/ US |
|---|---|---|
| Jardiance (alt SGLT2) | ~$550/mo | Alt SGLT2 brand |
| Walgreens | ~$750/mo | Save substantially |
| CVS Pharmacy | ~$800/mo | Save substantially |
| Walmart | ~$600/mo | Save substantially |
| Costco | ~$650/mo | Save substantially |
| Generic metformin (alt) | ~$4/mo | Very cheap generic foundation |
*Retail prices are estimates based on public data and vary by pharmacy. Coupon prices from GoodRx and SingleCare as of April 2026. AffordMyPrescriptions Advocacy Service bypasses pharmacy pricing entirely by using the manufacturer’s assistance program to secure your Invokamet — independent of dosage or retail price.
Our Pricing:
$69.95 Per month
1 Medications
$79.95 Per Month
2 Medications
$89.95 Per Month
3 Medications
$99.95 Per Month
4+ Medications
Why choose us For Your Invokamet Prescription Program?
The Invokamet Patient Assistance Program is free to apply. Our $69.95 per month covers full advocacy. Generic metformin is very cheap first-line. The SGLT2 inhibitor addition provides cardiovascular and renal protection benefits. Diabetes optimization with your endocrinology or primary care team.
Enroll
Complete a simple eligibility form so our team can determine if you may qualify for Invokamet assistance.
We Advocate
Our specialists gather documentation, complete applications, and coordinate with your prescriber and the assistance program.
Receive Medication
Once approved, your Invokamet is delivered through the assistance program while we manage refills and annual renewals.
Discount Coupons vs. Patient Assistance Programs
Many patients try discount cards first. Here’s why the Patient Assistance Program through AffordMyPrescriptions is the better long-term solution for Invokamet:
Limitations of Coupons
Prices fluctuate — savings aren’t guaranteed month-to-month
Copay accumulators may prevent savings from counting toward your deductible
Coupon cards expire and require constant renewal
Still $600–$800 per month even with the best discount
Cannot be used with Medicare, Medicaid, or government insurance
Advantages of PAP Through Us
Fixed $69.95/month — never changes regardless of retail price
- No expiration — continuous access as long as you qualify
Medication supplied directly through the assistance program
We manage all paperwork, refills, and annual renewals
Medicare Part D patients accepted
If denied, we explore alternative savings paths on your behalf
DO YOU QUALIFY?
Eligibility is generally determined by annual household income and insurance status. Most programs follow guidelines that include limits of up to $40,000 for individuals, $60,000 for couples, and $100,000 for larger families. Because requirements vary by program and household, we encourage you to contact AffordMyPrescriptions directly so we can review your specific situation and determine if you qualify for Invokamet assistance.
- You Are A U.S. Citizen Or Legal Resident
- You Have A Valid Invokamet Prescription From A Licensed U.S. Healthcare Provider
- You Are Uninsured, Underinsured, Or A Medicare Part D Beneficiary
- You Have Recently Experienced A Change In Financial Circumstances That Affects Your Ability To Pay
Understanding Invokamet:
Invokamet combines canagliflozin (SGLT2 inhibitor — reduces renal glucose reabsorption, promoting glucose excretion in urine) with metformin (foundation T2DM therapy — reduces hepatic gluconeogenesis and improves insulin sensitivity). The fixed-dose combination simplifies polypharmacy. Canagliflozin has demonstrated cardiovascular and renal protection benefits.
How It Works:
Type 2 diabetes involves insulin resistance and pancreatic beta-cell dysfunction. Modern management targets glucose control, cardiovascular risk reduction, renal protection, and weight. Newer classes (SGLT2 inhibitors, GLP-1 agonists) provide benefits beyond glucose control. Canagliflozin blocks sodium-glucose cotransporter 2 (SGLT2) in the renal proximal tubule — reducing glucose reabsorption and promoting glycosuria. It lowers HbA1c, promotes weight loss, and reduces blood pressure. The CANVAS and CREDENCE trials demonstrated cardiovascular and renal protection. Metformin reduces hepatic gluconeogenesis and improves peripheral insulin sensitivity — the foundation of T2DM therapy for 60+ years. The combination provides complementary mechanisms.
Form and Use:
Invokamet tablets containing canagliflozin (50 mg or 150 mg) + metformin (500 mg or 1000 mg). Twice daily with meals. An extended-release version (Invokamet XR) is available for once-daily dosing. Renal function monitoring. Diabetes team follow-up.
Generic Availability:
No generic Invokamet. Individual components: metformin (very cheap generic), canagliflozin (Invokana — brand). Other SGLT2 inhibitors: dapagliflozin (Farxiga — brand), empagliflozin (Jardiance — brand), ertugliflozin (Steglatro — brand). Other SGLT2/metformin combos: Xigduo XR (dapagliflozin/metformin), Synjardy (empagliflozin/metformin), Segluromet (ertugliflozin/metformin). Full T2DM armamentarium: metformin generic, sulfonylureas generic (glipizide, glimepiride, glyburide), pioglitazone generic, DPP-4 inhibitors, GLP-1 agonists (Ozempic, Trulicity, Rybelsus, Mounjaro — brand), insulins. American Diabetes Association resources.
Warnings:
Diabetic ketoacidosis (including euglycemic DKA — can occur even with normal glucose; discontinue if suspected), lower limb amputation (canagliflozin — assess and reduce risk factors), Fournier’s gangrene (necrotizing fasciitis of the perineum — rare but serious), volume depletion/hypotension, urinary tract infections, genital mycotic infections (yeast, especially in women), acute kidney injury (dose adjust for renal function), hyperkalemia, bone fractures, lactic acidosis (metformin — rare; avoid in severe renal impairment, hepatic disease, alcohol excess). Other: hypoglycemia (especially with insulin or sulfonylurea combinations), GI effects (metformin). Renal function monitoring. Avoid metformin near iodinated contrast studies.
FAQ (Frequently Asked Questions)
How much does Invokamet cost without insurance?
$600–$800 per month at retail pharmacy. Generic metformin costs $4 per month. Canagliflozin (Invokana) alone is $500–$600/month brand. Combining generic metformin + Invokana may be cheaper than the fixed-dose Invokamet.
What are the benefits of SGLT2 inhibitors beyond glucose control?
SGLT2 inhibitors demonstrated cardiovascular benefits (reduced major cardiac events, heart failure hospitalization) and renal protection (slowed CKD progression) in landmark trials — canagliflozin in CANVAS and CREDENCE. Now recommended for cardiovascular and renal protection in T2DM patients with cardiovascular disease, heart failure, or CKD.
How is Invokamet different from Jardiance or Farxiga?
All are SGLT2 inhibitors with a similar mechanism. Invokamet is canagliflozin + metformin. Jardiance is empagliflozin (Synjardy is empa/metformin). Farxiga is dapagliflozin (Xigduo XR is dapa/metformin). All effective; choice by prescriber preference and insurance.
What are the risks of SGLT2 inhibitors?
Diabetic ketoacidosis (including euglycemic DKA), Fournier’s gangrene (rare necrotizing perineal infection), lower limb amputation risk (canagliflozin), volume depletion/hypotension, UTIs and genital yeast infections (especially women), acute kidney injury, bone fracture, hyperkalemia. Metformin: lactic acidosis (rare), GI effects, long-term B12 deficiency.
Should I take metformin alone vs Invokamet?
Metformin is the foundation first-line T2DM therapy — very cheap generic. Adding an SGLT2 inhibitor is recommended for patients with cardiovascular disease, heart failure, or CKD (for CV/renal benefit) or additional glucose control needs. Invokamet simplifies polypharmacy. Discuss with your prescriber.
Take Control of Your Medication Costs
Modern type 2 diabetes therapy provides cardiovascular and renal protection beyond glucose control. Our advocacy team is ready — $69.95 per month, or free if we cannot help.
Submit Enrollment Form
Start free by filling out a simple online form.
Receive Welcome Call
Our specialist will contact you for a quick welcome call.
We Manage The Process
Our team handles everything, so you can focus on your health.